Hiratsuka M, Furukawa H, Iwanaga T, Tamura S, Yasuda T, Nakano H, Nakamori S, Ohigashi H, Kameyama M, Sasaki Y
Department of Surgery, Center for Adult Diseases, Osaka, Japan.
Gan To Kagaku Ryoho. 1994 Oct;21(14):2392-7.
We have been performing an extended operation for scirrhous gastric cancer, namely left upper abdominal exenteration plus Appleby's method, and compared the prognosis among macroscopic subtype classifications. The surgical procedure of left upper abdominal exenteration plus Appleby's method is to resect the neighboring organs of the stomach in an en bloc fashion. It consists of total gastrectomy, partial pancreatectomy, splenectomy, transverse colectomy, cholecystectomy, resection of the left adrenal gland, and ligation and resection of the common hepatic artery. D4 lymph node dissection is carried out. Extended operations were performed for 45 cases of P0-1 scirrhous gastric cancer in 1983-1990. There were 25, 17 and 3 cases of giant fold type, erosive type and stenotic type scirrhous gastric cancers, respectively. Positive lymph node metastases were found in 64% of giant fold type cases and 82% of erosive type cases. In Po, T3-4 cases, cytology of intraoperative peritoneal lavage was positive in 27% of giant fold type cases and 50% of erosive type cases. Although there were no obvious macroscopic invasions found during the operative procedure, later histological study showed invasion to the left adrenal gland in 14% of giant fold type cases and 0% of erosive type cases, and invasion to the transverse colon in 21% of giant fold type cases and 15% of fold type and erosive type scirrhous gastric cancer according to the histological invasion of transverse colon were 25% in positive cases and 27% in negative cases (p = 0.27), 0% in positive cases and 27% in negative cases (p = 0.27), respectively. In giant fold type scirrhous gastric cancer, the extended operation is favorable. In erosive type scirrhous gastric cancer, peritoneal dissemination is observed with a high incidence. Therefore, prophylactic therapy is significant.
我们一直在对硬癌型胃癌实施一种扩大手术,即左上腹脏器切除术加苹果比氏手术,并比较了宏观亚型分类之间的预后情况。左上腹脏器切除术加苹果比氏手术的手术步骤是将胃的相邻器官整块切除。它包括全胃切除术、部分胰腺切除术、脾切除术、横结肠切除术、胆囊切除术、左肾上腺切除术以及肝总动脉结扎和切除术。进行D4淋巴结清扫。1983年至1990年期间,对45例P0 - 1期硬癌型胃癌患者实施了扩大手术。其中巨皱襞型、糜烂型和狭窄型硬癌型胃癌分别有25例、17例和3例。巨皱襞型病例中64%发现有阳性淋巴结转移,糜烂型病例中82%发现有阳性淋巴结转移。在P0、T3 - 4期病例中,术中腹腔灌洗细胞学检查显示,巨皱襞型病例中有27%为阳性,糜烂型病例中有50%为阳性。尽管手术过程中未发现明显的宏观侵犯,但后来的组织学研究显示,巨皱襞型病例中有14%侵犯至左肾上腺,糜烂型病例中为0%;巨皱襞型病例中有21%侵犯至横结肠,糜烂型病例中有15%侵犯至横结肠。根据横结肠的组织学侵犯情况,巨皱襞型和糜烂型硬癌型胃癌阳性病例中为25%,阴性病例中为27%(p = 0.27);阳性病例中为0%,阴性病例中为27%(p = 0.27)。对于巨皱襞型硬癌型胃癌,扩大手术效果良好。对于糜烂型硬癌型胃癌,腹膜播散的发生率较高。因此,预防性治疗具有重要意义。