Trillo A, Guha A
Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Arch Pathol Lab Med. 1988 Jul;112(7):731-3.
Two case reports of solitary bronchial papillomas are presented. The histologic features of the lesions are those of squamous papillomas exhibiting prominent condylomatous changes. Immunoperoxidase stains revealed the presence of human papillomavirus antigens in the koilocytotic cells. Ultrastructural studies demonstrated possible intranuclear viral-size particles. Solitary condylomatous papillomas of the bronchus should be distinguished from solitary bronchial squamous papillomas that do not have condylomatous features. The rationale for this separation is the likelihood of a viral origin for these condylomatous papillomas and their potential for malignant change.
本文报告两例孤立性支气管乳头状瘤。病变的组织学特征为鳞状乳头状瘤，伴有显著的湿疣样改变。免疫过氧化物酶染色显示空泡化细胞中存在人乳头瘤病毒抗原。超微结构研究显示可能存在核内病毒大小的颗粒。支气管孤立性湿疣样乳头状瘤应与无湿疣样特征的孤立性支气管鳞状乳头状瘤相鉴别。这种区分的依据是这些湿疣样乳头状瘤可能起源于病毒及其恶变的可能性。
