Kemperman C J, Kuilman M, Njio L K
Department of Psychiatry, Academic Hospital, Utrecht, The Netherlands.
Eur Arch Psychiatry Neurol Sci. 1988;237(3):161-5. doi: 10.1007/BF00451284.
Since the serum potassium level is under beta 2-adrenergic influence, we studied serum potassium values on admission in psychiatric patients. Data are reported on 683 patients from nine major diagnostic groups. Among these nine groups significant differences were found concerning the mean serum potassium level and incidence of hypokalemia. Significant differences existed between the alcohol withdrawal and attempted suicide groups compared to the dysthymic, bipolar manic, schizophrenic and nonschizophrenic psychosis groups. Like alcohol withdrawal, attempted suicide is assumed to be a hyper-adrenergic state. Although the relative contribution of factors like nutritional state, aldosterone, insulin, and beta 2-receptor density or sensitivity is unclear, the catecholamine-potassium relationship deserves further study.
由于血清钾水平受β2 - 肾上腺素能影响，我们研究了精神科患者入院时的血清钾值。报告了来自九个主要诊断组的683例患者的数据。在这九个组中，发现平均血清钾水平和低钾血症发生率存在显著差异。与心境恶劣、双相躁狂、精神分裂症和非精神分裂症性精神病组相比，酒精戒断组和自杀未遂组之间存在显著差异。与酒精戒断一样，自杀未遂被认为是一种高肾上腺素能状态。虽然营养状况、醛固酮、胰岛素以及β2 - 受体密度或敏感性等因素的相对作用尚不清楚，但儿茶酚胺与钾的关系值得进一步研究。
