基因组学革命如何最终助力非洲。 - Suppr

How the genomics revolution could finally help Africa.

作者信息

Nordling Linda

出版信息

Nature. 2017 Apr 5;544(7648):20-22. doi: 10.1038/544020a.

DOI:10.1038/544020a

PMID:28383002

Abstract

摘要

相似文献

How the genomics revolution could finally help Africa.

Nature. 2017 Apr 5;544(7648):20-22. doi: 10.1038/544020a.

Genetics. Kidney disease is parasite-slaying protein's downside.

Science. 2010 Jul 16;329(5989):263. doi: 10.1126/science.329.5989.263.

Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis.

Lancet HIV. 2016 Nov;3(11):e510-e520. doi: 10.1016/S2352-3018(16)30091-1. Epub 2016 Sep 6.

Viremia and HIV Drug Resistance Among People Receiving Dolutegravir Versus Efavirenz-Based First-Line Antiretroviral Therapy.

J Acquir Immune Defic Syndr. 2024 Apr 15;95(5):e8-e11. doi: 10.1097/QAI.0000000000003385. Epub 2024 Mar 11.

Dolutegravir versus efavirenz in women starting HIV therapy in late pregnancy (DolPHIN-2): an open-label, randomised controlled trial.

Lancet HIV. 2020 May;7(5):e332-e339. doi: 10.1016/S2352-3018(20)30050-3.

Fetal biometry following in-utero exposure to dolutegravir-based or efavirenz-based antiretroviral therapy.

AIDS. 2020 Dec 1;34(15):2336-2337. doi: 10.1097/QAD.0000000000002674.

Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).

PLoS Med. 2019 Sep 20;16(9):e1002895. doi: 10.1371/journal.pmed.1002895. eCollection 2019 Sep.

The biology of APOL1 with insights into the association between APOL1 variants and chronic kidney disease.

Clin Exp Nephrol. 2014 Apr;18(2):238-42. doi: 10.1007/s10157-013-0907-4.

Short-cycle therapy (5 days on/2 days off) with a lamivudine + dolutegravir regimen in a cohort of virologically suppressed patients with HIV infection.

Int J Antimicrob Agents. 2021 Mar;57(3):106290. doi: 10.1016/j.ijantimicag.2021.106290. Epub 2021 Jan 26.

The next chapter for African genomics.

Nature. 2020 Feb;578(7795):350-354. doi: 10.1038/d41586-020-00454-1.

引用本文的文献

Population Pharmacogenomics for Health Equity.

Genes (Basel). 2023 Sep 22;14(10):1840. doi: 10.3390/genes14101840.

Evidence-based Medicine and Mechanistic Evidence: The Case of the Failed Rollout of Efavirenz in Zimbabwe.

J Med Philos. 2023 Jun 20;48(4):348-358. doi: 10.1093/jmp/jhad019.

Prostate Cancer Disparities and Management in Southern Africa: Insights into Practices, Norms and Values.

Cancer Manag Res. 2022 Dec 28;14:3567-3579. doi: 10.2147/CMAR.S382903. eCollection 2022.

Bridging the genomic data gap in Africa: implications for global disease burdens.

Global Health. 2022 Dec 9;18(1):103. doi: 10.1186/s12992-022-00898-2.

The Apportionment of Pharmacogenomic Variation: Race, Ethnicity, and Adverse Drug Reactions.

Med Res Arch. 2022 Sep;10(9). doi: 10.18103/mra.v10i9.2986. Epub 2022 Sep 20.

Role of Precision Oncology in Type II Endometrial and Prostate Cancers in the African Population: Global Cancer Genomics Disparities.

Int J Mol Sci. 2022 Jan 6;23(2):628. doi: 10.3390/ijms23020628.

HIV-1 and human genetic variation.

Nat Rev Genet. 2021 Oct;22(10):645-657. doi: 10.1038/s41576-021-00378-0. Epub 2021 Jun 24.

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.

Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0027521. doi: 10.1128/AAC.00275-21.

Genomics and bioinformatics capacity in Africa: no continent is left behind.

Genome. 2021 May;64(5):503-513. doi: 10.1139/gen-2020-0013. Epub 2021 Jan 12.

African genetic diversity and adaptation inform a precision medicine agenda.

Nat Rev Genet. 2021 May;22(5):284-306. doi: 10.1038/s41576-020-00306-8. Epub 2021 Jan 11.

本文引用的文献

Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index.

Obesity (Silver Spring). 2017 Apr;25(4):794-800. doi: 10.1002/oby.21804. Epub 2017 Mar 13.

Identification of Cadherin 2 () Mutations in Arrhythmogenic Right Ventricular Cardiomyopathy.

Circ Cardiovasc Genet. 2017 Apr;10(2). doi: 10.1161/CIRCGENETICS.116.001605.

Genomics is failing on diversity.

Nature. 2016 Oct 13;538(7624):161-164. doi: 10.1038/538161a.

APOL1 risk variants, race, and progression of chronic kidney disease.

N Engl J Med. 2013 Dec 5;369(23):2183-96. doi: 10.1056/NEJMoa1310345. Epub 2013 Nov 9.

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe.

Eur J Clin Pharmacol. 2008 Apr;64(4):357-65. doi: 10.1007/s00228-007-0412-3. Epub 2007 Dec 5.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

How the genomics revolution could finally help Africa.

作者信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献