National University of Singapore, Department of Biomedical Engineering, Singapore, Singapore.
Tsinghua University, School of Medicine, Department of Biomedical Engineering, Beijing, China.
J Biomed Opt. 2017 Apr 1;22(4):45005. doi: 10.1117/1.JBO.22.4.045005.
Diffuse optical spectroscopy (DOS) and imaging methods have been widely applied to noninvasive detection of brain activity. We have designed and implemented a low cost, portable, real-time one-channel time-resolved DOS system for neuroscience studies. Phantom experiments were carried out to test the performance of the system. We further conducted preliminary human experiments and demonstrated that enhanced sensitivity in detecting neural activity in the cortex could be achieved by the use of late arriving photons.
漫射光学光谱（DOS）和成像方法已广泛应用于脑活动的无创检测。我们设计并实现了一种低成本、便携式、实时单通道的时间分辨 DOS 系统，用于神经科学研究。进行了幻影实验以测试系统的性能。我们进一步进行了初步的人体实验，证明通过使用延迟到达的光子可以提高检测皮层中神经活动的灵敏度。
