Davis Gemma, Perks Alexandra, Liyanage Pemith, Staines Konrad
Oral Medicine, University of Bristol Dental Hospital, Bristol, UK
Oral Medicine, University of Bristol Dental Hospital, Bristol, UK.
BMJ Case Rep. 2017 Apr 6;2017:bcr-2016-218663. doi: 10.1136/bcr-2016-218663.
Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.
口腔毛状白斑（OHL）是一种与爱泼斯坦-巴尔病毒感染相关的口腔黏膜病变。它通常表现为免疫功能低下个体舌侧缘无症状、不可去除的白色斑块。从历史上看，OHL被认为是HIV感染的特征性表现；然而，现在它是一系列影响免疫功能的疾病中的一种既定现象。毛细胞白血病（HCL）是一种罕见的慢性B细胞淋巴增殖性疾病，以非典型细胞独特的细胞学特征命名。我们报告了首例发生在HCL患者中的OHL病例，该病例在血液系统恶性肿瘤缓解后消退。
