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用于生物数据分析的解析模糊方法。

Analytical fuzzy approach to biological data analysis.

作者信息

Zhang Weiping, Yang Jingzhi, Fang Yanling, Chen Huanyu, Mao Yihua, Kumar Mohit

机构信息

Department of Electronic Information Engineering, Nanchang University, 330031 Nanchang, China.

Mprobe Inc., 94303 Palo Alto, USA.

出版信息

Saudi J Biol Sci. 2017 Mar;24(3):563-573. doi: 10.1016/j.sjbs.2017.01.027. Epub 2017 Jan 25.

DOI:10.1016/j.sjbs.2017.01.027
PMID:28386181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5372457/
Abstract

The assessment of the physiological state of an individual requires an objective evaluation of biological data while taking into account both measurement noise and uncertainties arising from individual factors. We suggest to represent multi-dimensional medical data by means of an optimal fuzzy membership function. A carefully designed data model is introduced in a completely deterministic framework where uncertain variables are characterized by fuzzy membership functions. The study derives the analytical expressions of fuzzy membership functions on variables of the multivariate data model by maximizing the over-uncertainties-averaged-log-membership values of data samples around an initial guess. The analytical solution lends itself to a practical modeling algorithm facilitating the data classification. The experiments performed on the heartbeat interval data of 20 subjects verified that the proposed method is competing alternative to typically used pattern recognition and machine learning algorithms.

摘要

对个体生理状态的评估需要在考虑测量噪声和个体因素引起的不确定性的同时,对生物数据进行客观评估。我们建议通过最优模糊隶属函数来表示多维医学数据。在一个完全确定性的框架中引入了一个精心设计的数据模型,其中不确定变量由模糊隶属函数来表征。该研究通过最大化围绕初始猜测的数据样本的超不确定性平均对数隶属值,推导出多元数据模型变量上模糊隶属函数的解析表达式。该解析解适用于一种实用的建模算法,有助于数据分类。对20名受试者的心跳间期数据进行的实验验证了所提出的方法是通常使用的模式识别和机器学习算法的有力替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/632d9a1bb817/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/32e17777df0a/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/a323c6a88c6d/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/c04e56c5802b/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/f2c01ae568aa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/1dc0b45a5b4b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/a28804f73a4b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/632d9a1bb817/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/32e17777df0a/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/a323c6a88c6d/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/c04e56c5802b/fx3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/f2c01ae568aa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/1dc0b45a5b4b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/a28804f73a4b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18cf/5372457/632d9a1bb817/gr4.jpg

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本文引用的文献

1
A Stochastic Framework for Robust Fuzzy Filtering and Analysis of Signals-Part I.随机框架用于稳健模糊信号滤波和分析 - 第 I 部分。
IEEE Trans Cybern. 2016 May;46(5):1118-31. doi: 10.1109/TCYB.2015.2423657. Epub 2015 May 1.
2
An interpretable fuzzy rule-based classification methodology for medical diagnosis.一种用于医学诊断的基于模糊规则的可解释分类方法。
Artif Intell Med. 2009 Sep;47(1):25-41. doi: 10.1016/j.artmed.2009.05.003. Epub 2009 Jun 18.
3
Fuzzy techniques for subjective workload-score modeling under uncertainties.
不确定性条件下主观工作量评分建模的模糊技术
IEEE Trans Syst Man Cybern B Cybern. 2008 Dec;38(6):1449-64. doi: 10.1109/TSMCB.2008.927712.
4
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