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小儿癫痫——印度视角

Pediatric epilepsy - an Indian perspective.

作者信息

Udani Vrajesh

机构信息

Grant Medical College & JJ Group of Hospitals, PD Hinduja National Hospital and Bf Wadia Hospital for Children, Mumbai, India.

出版信息

Indian J Pediatr. 2005 Apr;72(4):309-313. doi: 10.1007/BF02724012.

Abstract

Prevalence studies from India suggest that epilepsy prevalence is similar to developed nations. Neurocysticercosis (NCC) predominates as an etiology. A large treatment gap is still a public health problem. Benign epilepsies and West syndrome appear to be underrepresented in studies on classification of seizures/syndromes. Febrile seizures prevalence in India is similar to other countries and appear to be as benign. Risk factors of intractable epilepsy (IE) in Indian studies include early age of onset, neurodevelopmental abnormalities and certain seizure types. Perinatal injuries underlie many IE. Many IE are not truly intractable and respond to simple therapeutic measures. The ketogenic diet and surgery are other methods now being used in Indian centers. Neurocysticercosis and neonatal hypoglycemic brain injury, two widely prevalent etiologies are reviewed in detail.

摘要

来自印度的患病率研究表明,癫痫患病率与发达国家相似。神经囊尾蚴病(NCC)是主要病因。巨大的治疗缺口仍是一个公共卫生问题。在癫痫发作/综合征分类研究中,良性癫痫和韦斯特综合征的占比似乎较低。印度的热性惊厥患病率与其他国家相似,且似乎同样为良性。印度研究中难治性癫痫(IE)的危险因素包括发病年龄早、神经发育异常和某些癫痫发作类型。围产期损伤是许多难治性癫痫的病因。许多难治性癫痫并非真正难治,对简单治疗措施有反应。生酮饮食和手术是印度各中心目前正在使用的其他方法。本文详细综述了两种广泛流行的病因——神经囊尾蚴病和新生儿低血糖脑损伤。

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