Department of Neurology, Himalayan Institute, Doiwala, Dehradun, India.
Neurol India. 2011 Jan-Feb;59(1):37-40. doi: 10.4103/0028-3886.76855.
Community-based studies of epilepsy in India have reported variable prevalence rates, 5-10/1000 population. Reasons for this wide variation in the prevalence rates are uncertain. Most of the earlier studies had not done appropriate investigations to establish the possible etiology.
To study the prevalence and etiological profile of active epilepsy in the rural population of Uttarakhand.
In this rural community-based study in the state of Uttarakhand, a door-to-door survey was conducted using validated questionnaire. All the suspected cases of epilepsy were examined by a neurologist to confirm the diagnosis of epilepsy and all the confirmed cases underwent contrast computed tomography (CT) scan and electroencephalography (EEG). Epilepsy and epilepsy syndromes were classified using the classifications proposed by the International League Against Epilepsy.
Of the 14,086 population studied, 141 cases of active epilepsy were detected giving a crude prevalence rate of 1%. After clinical evaluation and scanning, 35 (24.8%) were found to have seizure disorder active neurocysticercosis (NCC) and 14 (9.9%) had remote symptomatic seizures related to calcified granuloma. After excluding acute and remote symptomatic cases related to NCC, prevalence rate of epilepsy was 6.5/1000.
The study suggests that the region-specific prevalence rates of epilepsy in India are partly dependent on the prevalence of NCC in the given community. To some extent, this may be responsible for variable rates of epilepsy prevalence reported from different regions of the country.
印度的社区癫痫研究报告了不同的患病率，为 5-10/1000 人。导致这种患病率广泛变化的原因尚不确定。大多数早期研究没有进行适当的调查来确定可能的病因。
研究北阿坎德邦农村人口中活动性癫痫的患病率和病因谱。
在北阿坎德邦的这项农村社区基础研究中，使用经过验证的问卷进行了逐户调查。所有疑似癫痫的病例均由神经科医生进行检查以确认癫痫的诊断，所有确诊病例均进行对比计算机断层扫描（CT）和脑电图（EEG）检查。使用国际抗癫痫联盟提出的分类法对癫痫和癫痫综合征进行分类。
在所研究的 14086 人中，发现 141 例活动性癫痫，粗患病率为 1%。经过临床评估和扫描，发现 35 例（24.8%）患有活动性神经囊尾蚴病（NCC），14 例（9.9%）患有与钙化肉芽肿有关的远期症状性癫痫。排除与 NCC 相关的急性和远期症状性病例后，癫痫的患病率为 6.5/1000。
该研究表明，印度特定地区的癫痫患病率部分取决于该社区中 NCC 的流行情况。在某种程度上，这可能是导致该国不同地区报告的癫痫患病率存在差异的原因之一。
