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有物质使用障碍的女性的处方避孕药使用和依从性。

Prescription contraception use and adherence by women with substance use disorders.

机构信息

Center for Health Policy and Research, University of Massachusetts Medical School, Worcester, MA, USA.

Commonwealth Medicine, University of Massachusetts Medical School, Shrewsbury, MA, USA.

出版信息

Addiction. 2017 Sep;112(9):1638-1646. doi: 10.1111/add.13840. Epub 2017 May 22.

Abstract

BACKGROUND AND AIMS

Unintended pregnancy rates are high among women with substance use disorders (SUDs), which could be explained partly by lower use of and adherence to contraception. We aimed to test: (1) the association of SUD with prescription contraceptive use, contraceptive method selection and adherence; (2) whether practices participating in the Patient-Centered Medical Home Initiative (PCMHI) had better contraceptive use and adherence for patients with SUD; and (3) for differences in the association of SUD with adherence by type of contraceptive used.

DESIGN

Retrospective cohort analysis of claims and encounter data.

SETTING

Massachusetts, USA.

PARTICIPANTS

A total of 47 902 women aged 16-45 years enrolled in Medicaid or Commonwealth Care in Massachusetts between 2010 and 2014.

MEASUREMENTS

We examined three dependent variables: (1) use of a reversible prescription contraceptive during 2012; (2) the contraceptive methods used; and (3) the proportion of days covered by a prescription contraceptive in the year following the first prescription contraceptive claim. The primary predictor was diagnosed SUD, defined as at least one claim for an alcohol or drug use disorder.

FINDINGS

SUD was associated with lower rates of prescription contraceptive use during 2012 [19.2 versus 23.9%; adjusted odds ratio (aOR) = 0.79, P < 0.001]. SUD was associated with decreased selection of long-acting reversible contraception (LARC) compared with short-acting contraception (SARC) (42.8 versus 44.5%; aOR = 0.83, P = 0.011). There was no significant association between SUD and adherence (aOR = 0.84, P = 0.068). PCMHI enrollment did not alter the relationship between SUD and contraceptive use or adherence. Contraceptive method did not impact the relationship between SUD and adherence.

CONCLUSION

Women with substance use disorders are less likely to use prescription contraceptives, especially long-acting methods, but are not significantly less likely to adhere to them once prescribed than women without substance use disorders.

摘要

背景与目的

患有物质使用障碍(SUD)的女性意外怀孕率较高,这部分可以解释为她们较少使用和坚持使用避孕措施。我们旨在检验:(1)SUD 与处方避孕药使用、避孕方法选择和坚持使用的关联;(2)参与以患者为中心的医疗之家倡议(PCMHI)的实践是否为 SUD 患者提供了更好的避孕效果和坚持使用;(3)对于不同类型避孕措施使用与 SUD 坚持使用的关联差异。

设计

基于索赔和就诊数据的回顾性队列分析。

设置

美国马萨诸塞州。

参与者

共有 47902 名年龄在 16-45 岁之间的女性参加了马萨诸塞州 2010 年至 2014 年的医疗补助或联邦保健计划。

测量指标

我们检验了三个因变量:(1)2012 年期间使用可逆处方避孕药的情况;(2)使用的避孕方法;(3)首次开具处方避孕药后一年内,处方药覆盖的天数比例。主要预测因素是确诊的 SUD,定义为至少有一次酒精或药物使用障碍的索赔。

发现

SUD 与 2012 年期间处方避孕药使用率较低相关[19.2%比 23.9%;调整后的优势比(aOR)=0.79,P<0.001]。与短期避孕措施(SARC)相比,SUD 与长效可逆避孕措施(LARC)的选择减少相关(42.8%比 44.5%;aOR=0.83,P=0.011)。SUD 与坚持使用避孕药之间没有显著关联(aOR=0.84,P=0.068)。PCMHI 参与并未改变 SUD 与避孕措施使用或坚持使用之间的关系。避孕方法并未影响 SUD 与坚持使用避孕药之间的关系。

结论

患有物质使用障碍的女性使用处方避孕药的可能性较低,尤其是长效方法,但一旦开处方,她们坚持使用避孕药的可能性与没有物质使用障碍的女性相比并无显著差异。

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