Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of New Mexico, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131, USA; Department of Family and Community Medicine, School of Medicine, University of New Mexico, MSC09 5040, 1 University of New Mexico, Albuquerque, NM, 87131, USA.
Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of New Mexico, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131, USA.
Drug Alcohol Depend. 2018 Jun 1;187:305-310. doi: 10.1016/j.drugalcdep.2018.02.025. Epub 2018 Apr 10.
Prenatal care programs for women with opioid use disorder (OUD) often focus treatment/counseling plans around illicit substances, while concurrent use of alcohol might present an equal or greater risk to the fetus.
This study evaluated self-reported prevalence of alcohol use in patients participating in a comprehensive prenatal care program for women with substance use disorder (SUD; n = 295), of which 95% are treated for OUD, and pregnant women being served through general obstetrical clinics at the University of New Mexico (n = 365). During the screening phase of a prospective study, patients were asked to report alcohol use in the periconceptional period, and between the last menstrual period and pregnancy recognition.
The screening interview was conducted at 22.3 (median = 22; Q1 = 16; Q3 = 29) gestational weeks. Among patients screened at the SUD clinic, 28.8% and 24.1% reported at least one binge drinking episode in the periconceptional period and in early pregnancy, respectively. The prevalence of binge drinking was similar in the general obstetrics population (24.7% and 24.4%, respectively). Among those who reported drinking in early pregnancy, median number of binge drinking episodes was higher among patients screened at the SUD clinic (median = 3; Q1 = 1; Q3 = 10) compared to the general obstetrics group (median = 1; Q1 = 1; Q3 = 3; p < 0.001).
This study demonstrates a high prevalence of prenatal alcohol use in early pregnancy in both groups, while patients with SUD/OUD consume more alcohol. These findings underscore the need for targeted screening and intervention for alcohol use in all pregnant women, especially those with SUD/OUD.
针对患有阿片类药物使用障碍(OUD)的女性的产前护理项目通常侧重于治疗/咨询计划中的非法物质,而同时使用酒精可能对胎儿构成同等或更大的风险。
本研究评估了参加综合物质使用障碍(SUD)产前护理计划的患者(n=295)中自我报告的酒精使用流行率,其中 95%的患者接受 OUD 治疗,以及在新墨西哥大学接受普通产科诊所服务的孕妇(n=365)。在一项前瞻性研究的筛选阶段,患者被要求报告在围孕期和末次月经与妊娠识别之间的酒精使用情况。
筛选访谈在 22.3(中位数=22;Q1=16;Q3=29)妊娠周进行。在 SUD 诊所接受筛查的患者中,分别有 28.8%和 24.1%报告在围孕期和孕早期至少有一次 binge drinking 发作。在普通产科人群中,binge drinking 的患病率相似(分别为 24.7%和 24.4%)。在报告孕早期饮酒的人群中,在 SUD 诊所接受筛查的患者中 binge drinking 发作的中位数更高(中位数=3;Q1=1;Q3=10)与普通产科组(中位数=1;Q1=1;Q3=3;p<0.001)。
本研究表明,在两组中,孕早期都有很高的产前酒精使用流行率,而 SUD/OUD 患者的饮酒量更多。这些发现强调了需要针对所有孕妇,特别是 SUD/OUD 患者,进行针对性的酒精使用筛查和干预。