Activation-induced deoxycytidine deaminase: Structural basis for favoring WRC hot motif specificities unique among APOBEC family members.
作者信息
Pham Phuong, Afif Samir A, Shimoda Mayuko, Maeda Kazuhiko, Sakaguchi Nobuo, Pedersen Lars C, Goodman Myron F
机构信息
Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, United States.
Department of Immunology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan; Laboratory of Host Defence, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan; World Premier International Research Center Initiative, Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita 565-0871, Japan.
出版信息
DNA Repair (Amst). 2017 Jun;54:8-12. doi: 10.1016/j.dnarep.2017.03.007. Epub 2017 Mar 28.
Abstract
摘要
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A mathematical model for scanning and catalysis on single-stranded DNA, illustrated with activation-induced deoxycytidine deaminase.用于单链 DNA 扫描和催化的数学模型，以激活诱导的脱氧胞苷脱氨酶为例。
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