成瘾药物导致精神障碍症状改善的矛盾现象的生物学证据。
Biological Evidence for Paradoxical Improvement of Psychiatric Disorder Symptoms by Addictive Drugs.
机构信息
Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
出版信息
Trends Pharmacol Sci. 2017 Jun;38(6):501-502. doi: 10.1016/j.tips.2017.03.005. Epub 2017 Apr 4.
Addiction biology has focused on the mechanisms of the positive and negative reinforcing actions of addictive drugs but neglected potential benefits. Two new studies provide the first insights into a neurobiology of psychoactive drug instrumentalization. This may help us design better models for addiction neuroscience and opens a new dimension for the development of personalized pharmacotherapy of drug addiction.
成瘾生物学一直专注于成瘾药物的正性和负性强化作用的机制，但忽视了潜在的益处。两项新的研究提供了关于精神活性药物工具化神经生物学的最初见解。这可能有助于我们设计更好的成瘾神经科学模型，并为药物成瘾的个性化药物治疗开辟了新的维度。
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