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Live viral vaccines for respiratory and enteric tract diseases.

作者信息

Chanock R M, Murphy B R, Collins P L, Coelingh K V, Olmsted R A, Snyder M H, Spriggs M K, Prince G A, Moss B, Flores J

机构信息

Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.

出版信息

Vaccine. 1988 Apr;6(2):129-33. doi: 10.1016/s0264-410x(88)80014-8.

DOI:10.1016/s0264-410x(88)80014-8
PMID:2838984
Abstract

In its programme for accelerated development of vaccines for viral respiratory and enteric tract diseases the WHO has assigned a very high priority to respiratory syncytial virus (RSV), parainfluenza viruses and rotaviruses. There is also some interest in alternative approaches to immunization against influenza viruses because of the failure of inactivated vaccines to provide complete and reasonably durable immunity. Current attempts to develop satisfactorily attenuated viruses for use in prevention of disease caused by the above viral pathogens are described.

摘要

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