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催产素和加压素在Chang肝细胞培养中的印记作用:激素重叠、结合及对细胞分裂的影响

Imprinting with oxytocin and vasopressin in Chang liver cell cultures: hormonal overlap, binding and influence on cell division.

作者信息

Bohdaneczky E, Csaba G, Csiky J, Köhidai L

机构信息

Department of Biology, Semmelweis University Medical School, Budapest, Hungary.

出版信息

Acta Physiol Hung. 1988;71(1):35-40.

PMID:2839005
Abstract

In Chang liver cells the administration of oxytocin and vasopressin as well as the combined application of the two hormones will result in a positive binding imprinting for oxytocin and a negative binding imprinting for vasopressin. The hormones are able to increase the mitotic capacity of the liver cells even without previous imprinting, both in the case of treatment for 4 hours and for 24 hours; the change, however, is more marked in the case of treatment for 4 hours. Treatment for 24 hours results also in some functional imprinting.

摘要

在张氏肝细胞中,给予催产素和加压素以及联合应用这两种激素,将导致催产素出现正性结合印记,加压素出现负性结合印记。即使没有预先印记,这两种激素在处理4小时和24小时的情况下均能提高肝细胞的有丝分裂能力;然而,在处理4小时的情况下变化更为明显。处理24小时也会导致一些功能印记。

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