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实验性肝癌中的血清脯氨酰羟化酶蛋白

Serum prolyl hydroxylase protein in experimental liver cancer.

作者信息

Bolarin D M

机构信息

Department of Clinical Pathology, College of Medicine, Lagos University, Nigeria.

出版信息

Acta Physiol Hung. 1988;71(1):55-9.

PMID:2839006
Abstract

Total prolyl hydroxylase protein was measured in serum of rats fed with 0.06% of azodye, 3-methyl-4-dimethyl-aminoazobenzene (3-MeDAB). Serum enzyme protein values in the group progressing to primary hepatoma and those which had the tumors were significantly different (p less than 0.001) from the controls. The results suggest that the assay of serum prolyl hydroxylase protein may be an additional useful tool in the diagnosis of primary hepatic cancer.

摘要

在喂食0.06%偶氮染料3-甲基-4-二甲基氨基偶氮苯(3-MeDAB)的大鼠血清中检测总脯氨酰羟化酶蛋白。进展为原发性肝癌的组和患有肿瘤的组的血清酶蛋白值与对照组有显著差异(p小于0.001)。结果表明,血清脯氨酰羟化酶蛋白检测可能是原发性肝癌诊断中的一项额外有用工具。

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