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台湾社区老年人中轻度和重度抑郁症的患病率及危险因素。

Prevalence of and risk factors for minor and major depression among community-dwelling older adults in Taiwan.

机构信息

Department of Psychiatry,National Taiwan University Hospital,Taipei,Taiwan,ROC.

Aesthetic-Mind Clinic,Taichung,Taiwan,ROC.

出版信息

Int Psychogeriatr. 2017 Jul;29(7):1113-1121. doi: 10.1017/S1041610217000199. Epub 2017 Apr 9.

Abstract

BACKGROUND

This study was conducted to estimate prevalence rates and risk factors for late-life depression in a large nationwide representative sample from Taiwan.

METHODS

A total of 5,664, randomly sampled individuals aged ≥55 years were enrolled. Clinically, relevant depressive symptoms were classified using the Center for Epidemiological Studies Depression Scale (CES-D score ≥16), and major depression was confirmed using the Primary Care Evaluation of Mental Disorders. Individuals with clinically relevant depressive symptoms, who did not meet the strict diagnostic criteria for major depression, were considered to have minor depression. Multinomial logistic regression analyses were conducted to identify risk factors for major and minor depression, including socio-demographic characteristics, medical conditions, lifestyle behaviors, social support network, and life events.

RESULTS

The prevalence rates of minor and major depression were 3.7% and 1.5%, respectively. Major depression was associated with personal vulnerability factors, such as poor social support, cognitive impairment, comorbid pain conditions, and sleep disturbance. However, minor depression was more likely to be related to adverse life events, including increased burden on families, changes in health status, or relationship problem. Approximately, 20.0% of individuals with major depression received antidepressant treatment.

CONCLUSIONS

Late-life depression was less prevalent among community-dwelling older adults in Taiwan than among populations in other countries. Our findings may aid the early detection and treatment of late-life depression and provide a basis for future investigations.

摘要

背景

本研究旨在估计台湾一个大型全国代表性样本中老年抑郁症的患病率和危险因素。

方法

共纳入 5664 名年龄≥55 岁的随机抽样个体。临床方面,采用流行病学研究中心抑郁量表(CES-D 得分≥16)对相关抑郁症状进行分类,并采用初级保健精神障碍评估对重度抑郁症进行确诊。有临床相关抑郁症状但不符合重度抑郁症严格诊断标准的个体被认为患有轻度抑郁症。采用多项逻辑回归分析来确定重度和轻度抑郁症的危险因素,包括社会人口统计学特征、医疗状况、生活方式行为、社会支持网络和生活事件。

结果

轻度和重度抑郁症的患病率分别为 3.7%和 1.5%。重度抑郁症与个人脆弱因素有关,如社会支持差、认知障碍、合并疼痛疾病和睡眠障碍。然而,轻度抑郁症更可能与不良生活事件有关,包括家庭负担增加、健康状况变化或关系问题。约 20.0%的重度抑郁症患者接受了抗抑郁治疗。

结论

与其他国家的人群相比,台湾社区居住的老年人群中晚年抑郁症的患病率较低。我们的研究结果可能有助于早期发现和治疗晚年抑郁症,并为未来的研究提供基础。

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