Chen Xiaoyu, Yang Zaixing
Department of Emergency Room, Taizhou First People's Hospital, Huangyan Hospital of Wenzhou Medical University, Zhejiang, China.
Department of Laboratory Medicine, Taizhou First People's Hospital, Huangyan Hospital of Wenzhou Medical University, Zhejiang, China.
Am J Emerg Med. 2017 Aug;35(8):1209.e1-1209.e2. doi: 10.1016/j.ajem.2017.04.006. Epub 2017 Apr 3.
Propafenone is prescribed for the control of cardiac ventricular arrhythmias. Poisoning from propafenone intoxication is rare, but the survival rate of patients is low. We present a case of a 37-year-old man who developed cardiac arrest due to propafenone intoxication. Cardiopulmonary resuscitation, plasmapheresis, and other medical treatments had no effect on cardiac arrest. After repeated administrations of calcium gluconate, the patient achieved a full recovery. To the best of our knowledge, this is the first case report in which a full recovery from cardiac arrest was achieved by administration of calcium gluconate. We recommend that for patients poisoned by propafenone, close monitoring for decreased blood calcium is important.
普罗帕酮被用于控制心室心律失常。普罗帕酮中毒罕见，但患者的生存率较低。我们报告一例37岁男性因普罗帕酮中毒发生心脏骤停的病例。心肺复苏、血浆置换及其他治疗对心脏骤停均无效。在反复静脉注射葡萄糖酸钙后，患者完全康复。据我们所知，这是首例通过静脉注射葡萄糖酸钙使心脏骤停患者完全康复的病例报告。我们建议，对于普罗帕酮中毒患者，密切监测血钙降低情况很重要。
