Department of Oral and Maxillofacial Surgery, Navodaya Dental College and Hospital, Raichur, Karnataka, India.
Department of Oral and Maxillofacial Surgery, Bapuji Dental College and Hospital, Davangere, Karnataka, India.
J Oral Pathol Med. 2017 Jul;46(6):418-423. doi: 10.1111/jop.12583. Epub 2017 May 4.
Oral submucous fibrosis (OSMF) is a debilitating condition of oral cavity which has significant potential for malignant transformation. In spite of over 20 years of research, the pathogenesis of the condition is still obscure and no single management modality is effective. Many OSMF treatment protocols have been proposed to alleviate the signs and symptoms of the disorder and there is overwhelming evidence that as areca nut is primary cause, stopping its use may have a considerable effect on symptoms rather than reversing pre-existing fibrosis. We present a review of the current protocols for managing OSMF.
口腔黏膜下纤维化（OSMF）是一种口腔的进行性疾病，具有恶性转化的巨大潜力。尽管已经进行了 20 多年的研究，但该病的发病机制仍不清楚，也没有单一的治疗方法是有效的。已经提出了许多 OSMF 治疗方案来缓解该疾病的症状，并且有大量证据表明槟榔是主要原因，停止使用槟榔可能对症状有很大的影响，而不是逆转已经存在的纤维化。我们对目前治疗 OSMF 的方案进行了综述。
