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坏死性黄色肉芽肿性葡萄膜炎和巩膜炎的管理

Management of Uveitis and Scleritis in Necrobiotic Xanthogranuloma.

作者信息

Gonzales John A, Haemel Anna, Gross Andrew J, Acharya Nisha R

机构信息

1 F.I. Proctor Foundation, University of California , San Francisco, San Francisco, California.

2 Department of Ophthalmology, University of California , San Francisco, San Francisco, California.

出版信息

J Ocul Pharmacol Ther. 2017 May;33(4):325-333. doi: 10.1089/jop.2016.0135. Epub 2017 Apr 10.

Abstract

Necrobiotic xanthogranuloma (NXG) is a chronic, progressive non-Langerhans histiocytic granulomatous disease. While case reports describing periorbital involvement of NXG are frequent, only a few case reports describing ocular involvement, such as scleritis and uveitis, exist. Herein, we present a case presenting initially as bilateral anterior and posterior scleritis, as well as a chronic bilateral granulomatous panuveitis, and discuss the immunosuppressant options that should be considered for this disease with protean manifestations.

摘要

坏死性黄色肉芽肿(NXG)是一种慢性、进行性非朗格汉斯组织细胞肉芽肿性疾病。虽然描述NXG眶周受累的病例报告很常见,但描述眼部受累(如巩膜炎和葡萄膜炎)的病例报告却很少。在此,我们报告一例最初表现为双侧前巩膜炎和后巩膜炎以及慢性双侧肉芽肿性全葡萄膜炎的病例,并讨论针对这种具有多种表现形式的疾病应考虑的免疫抑制剂选择。

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