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地诺单抗在颞骨鳞状细胞复发性软骨母细胞瘤中的应用：一例报告

Use of denosumab in recurrent chondroblastoma of the squamous temporal bone: a case report.

作者信息

Calvert Nicholas, Wood David

机构信息

Department of Orthopaedic Surgery Sir Charles Gairdner Hospital Nedlands Western Australia 6009 Australia.

出版信息

Clin Case Rep. 2017 Feb 23;5(4):411-413. doi: 10.1002/ccr3.838. eCollection 2017 Apr.

DOI:10.1002/ccr3.838
PMID:28396758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5378851/
Abstract

Chondroblastoma is a rare, benign bone tumor that represents 1-2% of all primary bone tumors. Denosumab, a monoclonal antibody, has been demonstrated to inhibit the growth of giant cell tumors. We report a case of recurrent chondroblastoma of the squamous temporal bone that is currently suppressed with denosumab.

摘要

软骨母细胞瘤是一种罕见的良性骨肿瘤，占所有原发性骨肿瘤的1%-2%。地诺单抗是一种单克隆抗体，已被证明可抑制巨细胞瘤的生长。我们报告一例颞骨鳞部复发性软骨母细胞瘤，目前用地诺单抗控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/b29a04d2234e/CCR3-5-411-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/d87c42c29ed9/CCR3-5-411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/8113ac6f82bf/CCR3-5-411-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/b29a04d2234e/CCR3-5-411-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/d87c42c29ed9/CCR3-5-411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/8113ac6f82bf/CCR3-5-411-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06c9/5378851/b29a04d2234e/CCR3-5-411-g003.jpg

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Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone.地舒单抗可诱导骨巨细胞瘤患者肿瘤缩小和骨形成。
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地舒单抗治疗肱骨近端软骨母细胞瘤肺转移的疗效。
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A large invasive chondroblastoma on the temporomandibular joint and external auditory canal: a case report and literature review.颞下颌关节和外耳道的巨大侵袭性软骨母细胞瘤：一例报告并文献复习
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Rare chondroblastoma of the 6th left rib, video-assisted thoracoscopy resected: one case report and literature review.第六左肋罕见成软骨细胞瘤，胸腔镜辅助切除：一例报告及文献复习。
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Chondroblastoma's Lung Metastases Treated with Denosumab in Pediatric Patient.成软骨细胞瘤肺转移患儿接受地舒单抗治疗。
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地舒单抗治疗骨巨细胞瘤患者的开放性、2 期研究。
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