Lheureux S, Denoyelle C, Ohashi P S, De Bono J S, Mottaghy F M
Drug Development Program, Medical Oncology Princess Margaret Cancer Centre, Toronto, Canada.
Normandie Univ, UNICAEN, Inserm, ANTICIPE (Interdisciplinary Research for Cancers Prevention and Treatment, axis 2 BioTICLA (Biology and Innovative Therapeutics for Locally Aggressive Cancers), 14000, Caen, France.
Eur J Nucl Med Mol Imaging. 2017 Aug;44(Suppl 1):41-54. doi: 10.1007/s00259-017-3695-3. Epub 2017 Apr 10.
Molecular imaging continues to influence every aspect of cancer care including detection, diagnosis, staging and therapy response assessment. Recent advances in the understanding of cancer biology have prompted the introduction of new targeted therapy approaches. Precision medicine in oncology has led to rapid advances and novel approaches optimizing the use of imaging modalities in cancer care, research and development. This article focuses on the concept of targeted therapy in cancer and the challenges that exist for molecular imaging in cancer care.
分子成像继续影响癌症治疗的各个方面,包括检测、诊断、分期和治疗反应评估。对癌症生物学理解的最新进展促使了新的靶向治疗方法的引入。肿瘤学中的精准医学带来了快速进展和新方法,优化了成像模态在癌症治疗、研究和开发中的应用。本文重点关注癌症靶向治疗的概念以及癌症治疗中分子成像所面临的挑战。