Brunner F
Universitäre Klinik für Rheumatologie, Abteilung für Physikalische Medizin und Rheumatologie, Universitätsklinik Balgrist, Forchstr. 340, 8008, Zürich, Schweiz.
Z Rheumatol. 2017 May;76(4):335-347. doi: 10.1007/s00393-017-0299-z.
The term complex regional pain syndrome (CRPS) describes a variety of painful conditions, which typically occur distally on an extremity following an initiating event. Characteristically CRPS exceeds the expected clinical course in both magnitude and duration. Clinical manifestations of CRPS include sensory, vasomotor, sudomotor, motor and trophic disorders. The diagnosis of CRPS is purely clinical and based on the modified Budapest criteria. Essential differential diagnoses in the early phase include infections, neurological compression and inflammatory conditions. Although benign courses have been reported, many patients develop a chronic condition with persisting complaints even after 1 year. Therapy is based on a variety of pharmacological, interventional, physiotherapeutic, occupational and psychiatric treatment options.
复杂区域疼痛综合征（CRPS）这一术语描述了多种疼痛状况，这些状况通常在引发事件后出现在肢体远端。CRPS的特征是在严重程度和持续时间上均超出预期的临床病程。CRPS的临床表现包括感觉、血管运动、汗腺分泌、运动和营养障碍。CRPS的诊断完全基于临床，依据改良的布达佩斯标准进行。早期的主要鉴别诊断包括感染、神经受压和炎症性疾病。尽管有报告称病程呈良性，但许多患者会发展为慢性病，即使在1年后仍持续存在症状。治疗基于多种药物、介入、物理治疗、职业治疗和心理治疗选择。
