急性淋巴细胞白血病（ALL）中的一种新的染色体异常。
A new chromosome anomaly in acute lymphoblastic leukemia (ALL).
作者信息
Van den Berghe H, David G, Broeckaert-Van Orshoven A, Louwagie A, Verwilghen R, Casteels-Van Daele M, Eggermont E, Eeckels R
出版信息
Hum Genet. 1979 Jan 25;46(2):173-80. doi: 10.1007/BF00291919.
A new chromosome anomaly in acute lymphoblastic leukemia (ALL) is reported. Three, possibly four, patients showed an identical karyotype anomaly, characterized by a (4;11)(q13;q22) reciprocal translocation. This anomaly has not so far been found in lymphoproliferative disorders other than ALL. Two of the patients had congenital leukemia, but the anomaly described appears to be more characteristic of ALL than of congenital leukemia, and may help the clinician in establishing the diagnosis of ALL.
报告了急性淋巴细胞白血病（ALL）中的一种新的染色体异常。三名，可能四名患者显示出相同的核型异常，其特征为（4；11）（q13；q22）相互易位。迄今为止，在ALL以外的淋巴增生性疾病中尚未发现这种异常。两名患者患有先天性白血病，但所述异常似乎更具ALL的特征而非先天性白血病的特征，可能有助于临床医生确立ALL的诊断。
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