携带产毒艰难梭菌的血液肿瘤患者发生艰难梭菌感染的风险
Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile.
作者信息
Cannon Cara M, Musuuza Jackson S, Barker Anna K, Duster Megan, Juckett Mark B, Pop-Vicas Aurora E, Safdar Nasia
机构信息
1Department of Population Health Sciences,University of Wisconsin School of Medicine and Public Health,Madison,Wisconsin.
2Institute of Clinical and Translational Research,University of Wisconsin,Madison,Wisconsin.
出版信息
Infect Control Hosp Epidemiol. 2017 Jun;38(6):718-720. doi: 10.1017/ice.2017.48. Epub 2017 Apr 11.
Abstract
The prevalence of colonization with toxigenic Clostridium difficile among patients with hematological malignancies and/or bone marrow transplant at admission to a 566-bed academic medical care center was 9.3%, and 13.3% of colonized patients developed symptomatic disease during hospitalization. This population may benefit from targeted C. difficile infection control interventions. Infect Control Hosp Epidemiol 2017;38:718-720.
摘要
在一家拥有566张床位的学术医疗中心，血液系统恶性肿瘤患者和/或骨髓移植患者入院时产毒艰难梭菌的定植率为9.3%，定植患者中有13.3%在住院期间出现了症状性疾病。这一人群可能会从针对性艰难梭菌感染控制干预措施中获益。《感染控制与医院流行病学》2017年；38:718 - 720。
相似文献
1
Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile.
Infect Control Hosp Epidemiol. 2017 Jun;38(6):718-720. doi: 10.1017/ice.2017.48. Epub 2017 Apr 11.
2
Clostridium Difficile Colonization in Hematopoietic Stem Cell Transplant Recipients: A Prospective Study of the Epidemiology and Outcomes Involving Toxigenic and Nontoxigenic Strains.
Biol Blood Marrow Transplant. 2016 Jan;22(1):157-63. doi: 10.1016/j.bbmt.2015.07.020. Epub 2015 Jul 26.
3
Detection of toxigenic colonization in patients admitted to the hospital for chemotherapy or haematopoietic cell transplantation.
J Med Microbiol. 2018 Jul;67(7):976-981. doi: 10.1099/jmm.0.000774.
4
A retrospective review of metronidazole and vancomycin in the management of Clostridium difficile infection in patients with hematologic malignancies.
J Oncol Pharm Pract. 2014 Jun;20(3):172-82. doi: 10.1177/1078155213490004. Epub 2013 Jun 26.
5
Asymptomatic Clostridium difficile colonization as a reservoir for Clostridium difficile infection.
Expert Rev Anti Infect Ther. 2014 Aug;12(8):967-80. doi: 10.1586/14787210.2014.920252. Epub 2014 May 22.
6
Impact of Toxigenic Clostridium difficile Colonization on the Risk of Subsequent C. difficile Infection in Intensive Care Unit Patients.
Infect Control Hosp Epidemiol. 2015 Nov;36(11):1324-9. doi: 10.1017/ice.2015.177. Epub 2015 Jul 30.
7
Investigation of a Clostridium difficile cluster by multilocus sequence typing in a bone marrow transplant unit.
Am J Infect Control. 2014 Jun;42(6):691-3. doi: 10.1016/j.ajic.2014.02.008. Epub 2014 Mar 29.
8
Asymptomatic Carriers Contribute to Nosocomial Clostridium difficile Infection: A Cohort Study of 4508 Patients.
Gastroenterology. 2017 Apr;152(5):1031-1041.e2. doi: 10.1053/j.gastro.2016.12.035. Epub 2017 Jan 5.
9
Clostridium difficile rates in asymptomatic and symptomatic hospitalized patients using nucleic acid testing.
Diagn Microbiol Infect Dis. 2017 Apr;87(4):365-370. doi: 10.1016/j.diagmicrobio.2016.12.014. Epub 2017 Jan 3.
10
Asymptomatic carriers of toxigenic C. difficile in long-term care facilities: a meta-analysis of prevalence and risk factors.
PLoS One. 2015 Feb 23;10(2):e0117195. doi: 10.1371/journal.pone.0117195. eCollection 2015.
引用本文的文献
1
Heterogeneity of Clostridioides difficile asymptomatic colonization prevalence: a systematic review and meta-analysis.
Gut Pathog. 2025 Jan 27;17(1):6. doi: 10.1186/s13099-024-00674-0.
2
Oral vancomycin induced flushing syndrome in a multiple myeloma patient: A case report and review of the literature.
Medicine (Baltimore). 2024 Nov 22;103(47):e40640. doi: 10.1097/MD.0000000000040640.
3
infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options.
Clin Microbiol Rev. 2024 Jun 13;37(2):e0013523. doi: 10.1128/cmr.00135-23. Epub 2024 Feb 29.
4
Determination of Risk Factors for Infectious Diarrhea in Patients with Hematological Malignancy.
Infect Chemother. 2024 Jun;56(2):239-246. doi: 10.3947/ic.2023.0102. Epub 2024 Jan 18.
5
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
Antimicrob Steward Healthc Epidemiol. 2022 Apr 27;2(1):e72. doi: 10.1017/ash.2022.53. eCollection 2022.
6
Prevalence of Infection in the Hematopoietic Transplantation Setting: Update of Systematic Review and Meta-Analysis.
Front Cell Infect Microbiol. 2022 Feb 21;12:801475. doi: 10.3389/fcimb.2022.801475. eCollection 2022.
7
Clostridium difficile Colonization Before and After Hospitalization in Children.
Turk Arch Pediatr. 2021 Nov;56(6):585-590. doi: 10.5152/TurkArchPediatr.2021.21139.
8
Multi-organism gastrointestinal polymerase chain reaction positivity among pediatric transplant vs non-transplant populations: A single-center experience.
Pediatr Transplant. 2020 Sep;24(6):e13771. doi: 10.1111/petr.13771. Epub 2020 Jul 8.
9
Clostridioides difficile Infection in the Stem Cell Transplant and Hematologic Malignancy Population.
Infect Dis Clin North Am. 2019 Jun;33(2):447-466. doi: 10.1016/j.idc.2019.02.010.
10
A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases: 2005 - 2016.
BMC Infect Dis. 2019 Mar 21;19(1):274. doi: 10.1186/s12879-019-3901-y.
本文引用的文献
1
Clostridium difficile Infections amongst Patients with Haematological Malignancies: A Data Linkage Study.
PLoS One. 2016 Jun 17;11(6):e0157839. doi: 10.1371/journal.pone.0157839. eCollection 2016.
2
Clostridium Difficile Colonization in Hematopoietic Stem Cell Transplant Recipients: A Prospective Study of the Epidemiology and Outcomes Involving Toxigenic and Nontoxigenic Strains.
Biol Blood Marrow Transplant. 2016 Jan;22(1):157-63. doi: 10.1016/j.bbmt.2015.07.020. Epub 2015 Jul 26.
3
Colonization with toxinogenic C. difficile upon hospital admission, and risk of infection: a systematic review and meta-analysis.
Am J Gastroenterol. 2015 Mar;110(3):381-90; quiz 391. doi: 10.1038/ajg.2015.22. Epub 2015 Mar 3.
4
Effectiveness of screening hospital admissions to detect asymptomatic carriers of Clostridium difficile: a modeling evaluation.
Infect Control Hosp Epidemiol. 2014 Aug;35(8):1043-50. doi: 10.1086/677162. Epub 2014 Jun 20.
5
Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation.
Biol Blood Marrow Transplant. 2014 Sep;20(9):1329-34. doi: 10.1016/j.bbmt.2014.04.026. Epub 2014 May 2.
6
Clostridium difficile in a children's hospital: assessment of environmental contamination.
Am J Infect Control. 2014 Jul;42(7):802-4. doi: 10.1016/j.ajic.2014.03.008. Epub 2014 Apr 18.
7
Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA).
Infect Control Hosp Epidemiol. 2010 May;31(5):431-55. doi: 10.1086/651706.
8
Complete restriction of fluoroquinolone use to control an outbreak of Clostridium difficile infection at a community hospital.
Infect Control Hosp Epidemiol. 2009 Mar;30(3):264-72. doi: 10.1086/595694.
9
Antimicrobial-associated risk factors for Clostridium difficile infection.
Clin Infect Dis. 2008 Jan 15;46 Suppl 1:S19-31. doi: 10.1086/521859.
10
International typing study of toxin A-negative, toxin B-positive Clostridium difficile variants.
J Clin Microbiol. 2003 Apr;41(4):1543-7. doi: 10.1128/JCM.41.4.1543-1547.2003.
Zotero 插件