CD3 +、CD56 +、CD4 -、CD8 -、CD20 -、CD30 -外周T细胞非霍奇金淋巴瘤：一例罕见病例报告

Jagati Ashish, Shah Bela J, Tibrewal Sonal, Gajjar Trusha

Department of Skin and VD, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.

Indian J Dermatol. 2017 Mar-Apr;62(2):200-202. doi: 10.4103/ijd.IJD_440_16.

Cutaneous T-cell lymphoma (CTCL) commonly presents as mycosis fungoides or Sezary syndrome, both having CD4 positivity. A subset of CTCL which lacks CD4 surface marker is classified as cutaneous γ and δ-T-cell lymphoma (CGD-TCL). Because of its rarity and inability to study large number of patients, the impact of immunophenotype on the clinical outcome of primary CTCL in patients is limited. We report a case of primary CGD-TCL in a 71-year-old male because of this rarity and to emphasize its aggressive nature.

皮肤T细胞淋巴瘤（CTCL）通常表现为蕈样肉芽肿或塞扎里综合征，两者均为CD4阳性。缺乏CD4表面标志物的CTCL子集被归类为皮肤γ和δ-T细胞淋巴瘤（CGD-TCL）。由于其罕见性以及无法研究大量患者，免疫表型对原发性CTCL患者临床结局的影响有限。鉴于这种罕见性，我们报告了一例71岁男性原发性CGD-TCL病例，以强调其侵袭性。