• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

凝聚智慧:改善重症监护病房感染患者的治疗效果

Convergence of Minds: For Better Patient Outcome in Intensive Care Unit Infections.

作者信息

Wattal Chand, Javeri Yash, Goel Neeraj, Dhar Debashish, Saxena Sonal, Singh Sarman, Oberoi Jaswinder Kaur, Rao B K, Mathur Purva, Manchanda Vikas, Nangia Vivek, Kapil Arti, Rattan Ashok, Ghosh Supradip, Singh Omender, Singh Vinod, Kaur Iqbal, Datta Sanghamitra, Gupta Sharmila Sen

机构信息

Indian Association of Medical Microbiologists - Delhi Chapter, New Delhi, India.

Indian Society of Critical Care Medicine, New Delhi, India.

出版信息

Indian J Crit Care Med. 2017 Mar;21(3):154-159. doi: 10.4103/ijccm.IJCCM_365_16.

DOI:10.4103/ijccm.IJCCM_365_16
PMID:28400686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5363104/
Abstract

BACKGROUND

There is emergence of resistance to the last-line antibiotics such as carbapenems in Intensive Care Units (ICUs), leaving little effective therapeutic options. Since there are no more newer antibiotics in the armamentarium in the near future, it has become imperative that we harness the interdisciplinary knowledge for the best clinical outcome of the patient.

AIMS

The aim of the conference was to utilize the synergies between the clinical microbiologists and critical care specialists for better patient care and clinical outcome.

MATERIALS AND METHODS

A combined continuing medical education program (CME) under the aegis of the Indian Association of Medical Microbiologists - Delhi Chapter and the Indian Society of Critical Care Medicine, Delhi and national capital region was organized to share their expertise on the various topics covering epidemiology, diagnosis, management, and prevention of hospital-acquired infections in ICUs.

RESULTS

It was agreed that synergy between the clinical microbiologists and critical care medicine is required in understanding the scope of laboratory tests, investigative pathway testing, hospital epidemiology, and optimum use of antibiotics. A consensus on the use of rapid diagnostics such as point-of-care tests, matrix-assisted laser desorption ionization-time of flight mass spectrometry, and molecular tests for the early diagnosis of infectious disease was made. It was agreed that stewardship activities along with hospital infection control practices should be further strengthened for better utilization of the antibiotics. Through this CME, we identified the barriers and actionables for appropriate antimicrobial usage in Indian ICUs.

CONCLUSIONS

A close coordination between clinical microbiology and critical care medicine opens up avenues to improve antimicrobial prescription practices.

摘要

背景

重症监护病房(ICU)中出现了对碳青霉烯类等最后一线抗生素的耐药性,使得有效的治疗选择所剩无几。由于在不久的将来药库中不会有更新的抗生素,因此利用跨学科知识以实现患者最佳临床结局变得势在必行。

目的

本次会议的目的是利用临床微生物学家和重症监护专家之间的协同作用,以提供更好的患者护理并改善临床结局。

材料与方法

在印度医学微生物学家协会德里分会以及德里和国家首都地区的印度重症监护医学学会的支持下,组织了一个联合继续医学教育项目(CME),以分享他们在涵盖ICU医院获得性感染的流行病学、诊断、管理和预防等各个主题方面的专业知识。

结果

与会者一致认为,临床微生物学家和重症监护医学之间需要协同合作,以了解实验室检测的范围、调查途径检测、医院流行病学以及抗生素的最佳使用。就使用即时检验、基质辅助激光解吸电离飞行时间质谱等快速诊断方法以及用于传染病早期诊断的分子检测达成了共识。与会者一致认为,应进一步加强管理活动以及医院感染控制措施,以更好地利用抗生素。通过这次CME,我们确定了印度ICU中合理使用抗菌药物的障碍和可行措施。

结论

临床微生物学和重症监护医学之间的密切协调为改善抗菌药物处方实践开辟了道路。

相似文献

1
Convergence of Minds: For Better Patient Outcome in Intensive Care Unit Infections.凝聚智慧:改善重症监护病房感染患者的治疗效果
Indian J Crit Care Med. 2017 Mar;21(3):154-159. doi: 10.4103/ijccm.IJCCM_365_16.
2
Sepsis Care Pathway 2019.2019年脓毒症护理路径
Qatar Med J. 2019 Nov 7;2019(2):4. doi: 10.5339/qmj.2019.qccc.4. eCollection 2019.
3
Tuberculosis结核病
4
Cost Analysis of Implementing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Plus Real-Time Antimicrobial Stewardship Intervention for Bloodstream Infections.实施基质辅助激光解吸电离飞行时间质谱联用实时抗菌药物管理干预措施治疗血流感染的成本分析
J Clin Microbiol. 2016 Dec 28;55(1):60-67. doi: 10.1128/JCM.01452-16. Print 2017 Jan.
5
Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia.快速诊断与抗菌药物管理的整合可改善抗生素耐药革兰氏阴性菌血症患者的结局。
J Infect. 2014 Sep;69(3):216-25. doi: 10.1016/j.jinf.2014.05.005. Epub 2014 May 17.
6
A nationwide survey of intravenous antimicrobial use in intensive care units in Japan.日本重症监护病房静脉内抗菌药物使用的全国性调查。
Int J Antimicrob Agents. 2018 Apr;51(4):636-641. doi: 10.1016/j.ijantimicag.2018.01.022. Epub 2018 Feb 2.
7
Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs.快速病原体鉴定与抗菌药物管理的整合,可显著降低医院成本。
Arch Pathol Lab Med. 2013 Sep;137(9):1247-54. doi: 10.5858/arpa.2012-0651-OA. Epub 2012 Dec 6.
8
New and novel rapid diagnostics that are impacting infection prevention and antimicrobial stewardship.新型快速诊断技术正在影响感染预防和抗菌药物管理。
Curr Opin Infect Dis. 2019 Aug;32(4):356-364. doi: 10.1097/QCO.0000000000000565.
9
Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance.重症监护病房中的抗菌药物耐药性和抗生素管理计划:在抗耐药斗争中的坚持和持续努力。ESICM/ESCMID/WAAAR 多药耐药圆桌会议立场声明。
Intensive Care Med. 2018 Feb;44(2):189-196. doi: 10.1007/s00134-017-5036-1. Epub 2017 Dec 29.
10
Effect of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Alone versus MALDI-TOF MS Combined with Real-Time Antimicrobial Stewardship Interventions on Time to Optimal Antimicrobial Therapy in Patients with Positive Blood Cultures.基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)单独使用与MALDI-TOF MS联合实时抗菌药物管理干预措施对血培养阳性患者达到最佳抗菌治疗时间的影响。
J Clin Microbiol. 2017 May;55(5):1437-1445. doi: 10.1128/JCM.02245-16. Epub 2017 Feb 22.

引用本文的文献

1
Analysis of Blood Culture Data Influences Future Epidemiology of Bloodstream Infections: A 5-year Retrospective Study at a Tertiary Care Hospital in India.血培养数据分析对血流感染未来流行病学的影响:印度一家三级护理医院的5年回顾性研究
Indian J Crit Care Med. 2021 Nov;25(11):1258-1262. doi: 10.5005/jp-journals-10071-23922.
2
Clinical Outcome of Patients on Ceftazidime-Avibactam and Combination Therapy in Carbapenem-resistant Enterobacteriaceae.头孢他啶-阿维巴坦及联合治疗耐碳青霉烯类肠杆菌科细菌感染患者的临床结局
Indian J Crit Care Med. 2021 Jul;25(7):780-784. doi: 10.5005/jp-journals-10071-23863.

本文引用的文献

1
Issues in antifungal stewardship: an opportunity that should not be lost.抗真菌药物管理中的问题:一个不容错过的机遇。
J Antimicrob Chemother. 2017 Apr 1;72(4):969-974. doi: 10.1093/jac/dkw506.
2
Prevalence of Multidrug-resistant, Extensively Drug-resistant, and Pandrug-resistant from a Tertiary Level Intensive Care Unit.三级重症监护病房中多重耐药、广泛耐药和全耐药的发生率
J Glob Infect Dis. 2016 Oct-Dec;8(4):155-159. doi: 10.4103/0974-777X.192962.
3
Emergence of plasmid-mediated colistin resistance and New Delhi metallo-β-lactamase genes in extensively drug-resistant Escherichia coli isolated from a patient in Thailand.在泰国一名患者分离出的广泛耐药大肠杆菌中出现质粒介导的黏菌素耐药性和新德里金属β-内酰胺酶基因。
Diagn Microbiol Infect Dis. 2017 Feb;87(2):157-159. doi: 10.1016/j.diagmicrobio.2016.11.005. Epub 2016 Nov 14.
4
Executive Summary: Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.执行摘要:实施抗生素管理计划:美国传染病学会和美国医疗保健流行病学学会的指南。
Clin Infect Dis. 2016 May 15;62(10):1197-1202. doi: 10.1093/cid/ciw217.
5
Executive Summary: Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.执行摘要:《念珠菌病管理临床实践指南:美国传染病学会2016年更新版》
Clin Infect Dis. 2016 Feb 15;62(4):409-17. doi: 10.1093/cid/civ1194.
6
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.中国动物和人类中出现的质粒介导的粘菌素耐药机制 MCR-1:微生物学和分子生物学研究。
Lancet Infect Dis. 2016 Feb;16(2):161-8. doi: 10.1016/S1473-3099(15)00424-7. Epub 2015 Nov 19.
7
In Vitro Activities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli.头孢他啶-阿维巴坦、氨曲南-阿维巴坦以及一组较老和当代抗菌药物对产碳青霉烯酶革兰氏阴性杆菌的体外活性
Antimicrob Agents Chemother. 2015 Dec;59(12):7842-6. doi: 10.1128/AAC.02019-15. Epub 2015 Sep 21.
8
Evaluation of Four Commercial Multiplex Molecular Tests for the Diagnosis of Acute Respiratory Infections.四种用于诊断急性呼吸道感染的商用多重分子检测方法的评估
PLoS One. 2015 Jun 24;10(6):e0130378. doi: 10.1371/journal.pone.0130378. eCollection 2015.
9
Comparison of the Effectiveness and Safety of Linezolid and Daptomycin in Vancomycin-Resistant Enterococcal Bloodstream Infection: A National Cohort Study of Veterans Affairs Patients.利奈唑胺与达托霉素治疗耐万古霉素肠球菌血流感染的有效性和安全性比较:一项针对退伍军人事务部患者的全国队列研究
Clin Infect Dis. 2015 Sep 15;61(6):871-8. doi: 10.1093/cid/civ444. Epub 2015 Jun 10.
10
Antimicrobial heteroresistance: an emerging field in need of clarity.抗菌异质性耐药:一个亟待明确的新兴领域。
Clin Microbiol Rev. 2015 Jan;28(1):191-207. doi: 10.1128/CMR.00058-14.