Gupta A K, Sarin G S, Mathur M D, Ghosh B
Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.
Br J Ophthalmol. 1988 May;72(5):390-3. doi: 10.1136/bjo.72.5.390.
The alpha 1-antitrypsin and serum albumin levels in tear fluids were measured by electroimmunodiffusion in 76 healthy subjects and 63 patients with acute adenovirus conjunctivitis. They were found to be significantly increased during the acute phase of the disease. There was a correlation between increased severity of disease and increased levels of both the proteins. There was no significant difference in the tear alpha 1-antitrypsin and serum albumin levels in viral isolation-positive and isolation-negative patients. The raised levels of the two proteins in tears may reflect conjunctival inflammation rather than infection, since both isolation-positive and isolation-negative patients had the raised levels. The levels of the two proteins returned to normal with clinical improvement.
采用电免疫扩散法检测了76名健康受试者和63例急性腺病毒结膜炎患者泪液中的α1 -抗胰蛋白酶和血清白蛋白水平。发现在疾病急性期这些水平显著升高。疾病严重程度增加与这两种蛋白质水平升高之间存在相关性。病毒分离阳性和阴性患者的泪液α1 -抗胰蛋白酶和血清白蛋白水平无显著差异。泪液中这两种蛋白质水平升高可能反映的是结膜炎症而非感染，因为病毒分离阳性和阴性患者的这两种蛋白质水平均升高。随着临床症状改善，这两种蛋白质水平恢复正常。
