Sorsa T, Suomalainen K, Turto H, Lindy S
Department of Medical Chemistry, University of Helsinki, Finland.
Biosci Rep. 1987 Dec;7(12):965-8. doi: 10.1007/BF01122130.
Gold thioglucose and gold sodium thiomalate were shown to be potent activators of latent human leukocyte collagenase. No activation by auranofin was noted. The activation may proceed through the action of gold on the essential sulfhydryl groups of latent enzyme and, thereby, mimick the action of the known organomercurial activators.
硫代葡萄糖金和硫代苹果酸金钠被证明是潜在的人类白细胞胶原酶的有效激活剂。未观察到金诺芬有激活作用。这种激活可能是通过金对潜在酶的必需巯基的作用而进行的，从而模拟已知有机汞激活剂的作用。
