Huang Alice E, Montoya Juan C, Shiung Maria, Leng Shuai, McCollough Cynthia H
1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
AJR Am J Roentgenol. 2017 Jul;209(1):116-121. doi: 10.2214/AJR.16.16940. Epub 2017 Apr 12.
The objective of this prospective study is to evaluate the consistency of renal stone volume estimation using dual-energy CT across scanner model and reconstruction algorithm configurations.
Patients underwent scanning with routine kidney stone composition protocols on both second- and third-generation dual-source CT scanners. Images were reconstructed using filtered back projection and iterative reconstruction (IR). In addition, a modified IR kernel on the third-generation CT scanner was evaluated. Individual kidney stone volumes were determined and compared.
No significant difference was noted in measured volumes between filtered back-projection data, IR data from the second-generation scanner, and the modified IR kernel data (p > 0.05). The third-generation commercially available IR kernel yielded lower volumes than did the other configurations (p < 0.0001).
With the use of a modified kernel for the third-generation scanner, patients being monitored for changes in kidney stone volume can undergo scanning performed with second- or third-generation dual-energy CT scanners, and the images obtained can be reconstructed with either filtered back projection or IR without the introduction of bias into kidney stone volume measurements.
本前瞻性研究的目的是评估在不同扫描仪型号和重建算法配置下，使用双能CT估算肾结石体积的一致性。
患者在第二代和第三代双源CT扫描仪上均采用常规肾结石成分分析方案进行扫描。图像采用滤波反投影法和迭代重建（IR）法重建。此外，还对第三代CT扫描仪上的一种改良IR内核进行了评估。确定并比较了各个肾结石的体积。
滤波反投影数据、第二代扫描仪的IR数据与改良IR内核数据之间的测量体积无显著差异（p>0.05）。第三代商用IR内核得出的体积比其他配置的体积小（p<0.0001）。
对于第三代扫描仪使用改良内核的情况，监测肾结石体积变化的患者可采用第二代或第三代双能CT扫描仪进行扫描，所获得的图像可用滤波反投影法或IR法重建，而不会在肾结石体积测量中引入偏差。
