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激光辅助光动力疗法:两种提高治疗效果的新方案。

Laser-Assisted Photodynamic Therapy: Two Novel Protocols for Enhanced Treatment Results.

作者信息

Stevenson Mary L, Karen Julie K, Hale Elizabeth K

出版信息

J Drugs Dermatol. 2017 Apr 1;16(4):329-331.

Abstract

Photodynamic therapy (PDT) uses a topical photosensitizing agent which is activated by a light source to cause destruction of specific cells. Commonly used for the treatment of actinic keratoses and photodamage, PDT can also be used for other conditions including acne and sebaceous hyperplasia. Here we report our experience with two treatment protocols. The first protocol utilizes laser assisted delivery of topical 5-aminolevulinic acid for enhanced efficacy of blue light photodynamic therapy in the treatment of actinic keratoses and photodamage. The second protocol utilizes red light photodynamic therapy followed by pulsed dye laser to effectively target sebaceous glands in patients with extensive sebaceous hyperplasia.

J Drugs Dermatol. 2017;16(4):329-331.

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摘要

光动力疗法(PDT)使用一种局部光敏剂,该光敏剂由光源激活以破坏特定细胞。PDT通常用于治疗光化性角化病和光损伤,也可用于其他病症,包括痤疮和皮脂腺增生。在此,我们报告我们在两种治疗方案中的经验。第一种方案利用激光辅助递送局部5-氨基酮戊酸,以提高蓝光光动力疗法治疗光化性角化病和光损伤的疗效。第二种方案采用红光光动力疗法,随后进行脉冲染料激光治疗,以有效靶向广泛皮脂腺增生患者的皮脂腺。

《皮肤药物学杂志》。2017年;16(4):329 - 331。

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