Sandoval-Sus Jose D, Sotomayor Eduardo M, Shah Bijal D
Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Department of Hematology/Oncology, George Washington University, Washington, D.C., USA.
Hematol Oncol Stem Cell Ther. 2017 Sep;10(3):99-115. doi: 10.1016/j.hemonc.2017.02.003. Epub 2017 Apr 6.
Mantle cell lymphoma is a clinically heterogeneous disease occurring within a heterogeneous patient population, highlighting a need for personalized therapy to ensure optimal outcomes. It is therefore critical to understand the benefits and risks associated with both intensive and deintensified approaches. In the following review we provide a therapeutic roadmap to strategically guide treatment for newly diagnosed and relapsed/refractory patients highlighting pivotal and recently published results involving known and novel therapies.
套细胞淋巴瘤是一种发生在异质性患者群体中的临床异质性疾病,这凸显了个性化治疗以确保最佳治疗效果的必要性。因此,了解强化和弱化治疗方法的益处和风险至关重要。在以下综述中,我们提供了一个治疗路线图,以战略性地指导新诊断和复发/难治性患者的治疗,重点介绍涉及已知和新型疗法的关键及近期发表的结果。