Rossi Roberta Elisa, Conte Dario, Elli Luca, Branchi Federica, Massironi Sara
Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy.
Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Italy; Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Italy.
United European Gastroenterol J. 2017 Feb;5(1):5-12. doi: 10.1177/2050640616658220. Epub 2016 Jul 8.
The diagnosis of small-bowel neuroendocrine tumors (SbNETs) has improved with the advent of video capsule endoscopy (CE) and double-balloon enteroscopy (DBE). The data describing the efficacy of CE/DBE in the detection of SbNETs are scanty.
The aim of this article is to review the current evidence on the role of DBE and CE in the diagnosis of SbNETs.
A bibliographical search was performed in PubMed using the following keywords: "neuroendocrine tumors and enteroscopy/and capsule endoscopy" and "small bowel neuroendocrine tumors."
CE and DBE can be complementary and show a similar diagnostic yield. The number of false-negative results has not been established yet because of the "work-up bias" observed in the majority of the studies.
DBE and CE appear to be both safe and effective procedures useful in the diagnosis of SbNETs. Further studies are required to clarify their potential complications and relationship with other techniques, particularly nuclear imaging.
随着视频胶囊内镜（CE）和双气囊小肠镜（DBE）的出现，小肠神经内分泌肿瘤（SbNETs）的诊断得到了改善。描述CE/DBE在检测SbNETs中疗效的数据很少。
本文旨在综述当前关于DBE和CE在SbNETs诊断中作用的证据。
在PubMed中使用以下关键词进行文献检索：“神经内分泌肿瘤与小肠镜/和胶囊内镜”以及“小肠神经内分泌肿瘤”。
CE和DBE可以互补，并且显示出相似的诊断率。由于在大多数研究中观察到“检查偏倚”，假阴性结果的数量尚未确定。
DBE和CE似乎都是用于SbNETs诊断的安全有效的方法。需要进一步研究以阐明它们的潜在并发症以及与其他技术（特别是核成像）的关系。
