Garcia Jeanette M, Cox Daniel, Rice David J
Department of Education and Human Services , University of Central Florida , Orlando, Florida , USA.
Departments of Psychiatry, Internal Medicine, and Opthalmology , University of Virginia , Charlottesville, Virginia , USA.
BMJ Open Diabetes Res Care. 2017 Mar 29;5(1):e000306. doi: 10.1136/bmjdrc-2016-000306. eCollection 2017.
To examine the association between change in moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SB) over a 6-month period with physiological and psychological factors in adults with type 2 diabetes (T2D).
Participants included 26 middle-aged (mean age=56.1±10.8 years; 42% women), overweight/obese (mean body mass index (BMI) =37.22±8.78 kg/m) adults who had been diagnosed with T2D within the past 5 years (mean HbA1c=7.81%). Participants underwent a physical examination, blood tests, and psychological questionnaires, including a self-report questionnaire that assessed the consumption of high glycemic and low glycemic load foods. Participants wore an Actigraph accelerometer for 7 days to assess MVPA and SB. All measures were collected at baseline and at the 6-month follow-up. Spearman rank correlations and regression models were conducted to examine the relationship between activity variables, and the association of activity measures with health outcomes at the 6-month follow-up.
Decreases in duration of SB bouts and increases in MVPA were associated with decreased levels of HbA1c (p<0.05). Over 50% of the variance in HbA1c levels could be attributed to changes in MVPA and SB.
MVPA and SB were independently associated with diabetes-related health outcomes. Results suggest that emphasis should be placed on increasing MVPA while decreasing SB, particularly duration of SB bouts. This suggests that even small changes in daily behavior may contribute to improvement in diabetes-related health outcomes.
探讨2型糖尿病（T2D）成人在6个月期间中等到剧烈身体活动（MVPA）和久坐行为（SB）的变化与生理和心理因素之间的关联。
参与者包括26名中年（平均年龄=56.1±10.8岁；42%为女性）、超重/肥胖（平均体重指数（BMI）=37.22±8.78kg/m）的成年人，他们在过去5年内被诊断为T2D（平均糖化血红蛋白（HbA1c）=7.81%）。参与者接受了体格检查、血液检查和心理问卷调查，包括一份自我报告问卷，该问卷评估了高血糖和低血糖负荷食物的摄入量。参与者佩戴Actigraph加速度计7天以评估MVPA和SB。所有测量均在基线和6个月随访时收集。进行Spearman等级相关性分析和回归模型分析，以检验活动变量之间的关系，以及在6个月随访时活动测量与健康结果之间的关联。
SB发作持续时间的减少和MVPA的增加与HbA1c水平的降低相关（p<0.05）。HbA1c水平超过50%的变异可归因于MVPA和SB的变化。
MVPA和SB与糖尿病相关的健康结果独立相关。结果表明，应强调增加MVPA同时减少SB，尤其是SB发作的持续时间。这表明即使日常行为的微小变化也可能有助于改善糖尿病相关的健康结果。
