Tannier C, Hamidou M, Morlock G, Pages M
Service de neurologie, Centre Hospitalier de Carcassonne, France.
Neurophysiol Clin. 1988 Jun;18(3):285-90. doi: 10.1016/s0987-7053(88)80032-7.
A case of Eaton-Lambert myasthenic syndrome associated with inappropriate secretion of antidiuretic hormone is reported. This case included a demyelinizing peripheral neuropathy and was related to a small-cell carcinoma of the lung. Twelve similar cases appeared in the literature, most of them associated with small-cell carcinoma or undifferentiated lung tumors. Etiologic and diagnostic aspects of these syndromes are discussed. When isolated, their causes are various, including the classic context of the paraneoplastic syndromes. Their association is highly suggestive of a lung carcinoma and must enable to make an early diagnosis by use of all possible means of detection.
报告了一例伊顿-兰伯特肌无力综合征合并抗利尿激素分泌不当的病例。该病例包括脱髓鞘性周围神经病，且与肺小细胞癌有关。文献中出现了12例类似病例，其中大多数与小细胞癌或未分化肺肿瘤有关。讨论了这些综合征的病因及诊断方面。当这些综合征单独出现时，其病因多种多样，包括副肿瘤综合征的典型情况。它们的关联强烈提示肺癌，必须通过所有可能的检测手段进行早期诊断。
