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一例导致严重毁容的巨大乳腺叶状肿瘤。病例报告。

A giant phyllodes tumor of the breast causing severe disfigurement. A case report.

作者信息

Franceschini Gianluca, Di Giorgio Danilo, D'Archi Sabatino, Di Leone Alba, Sanchez Alejandro Martin, Masetti Riccardo

出版信息

Ann Ital Chir. 2017 Jan 20;6:S2239253X17026342.

Abstract

UNLABELLED

Phyllodes tumours (PTs) are rare fibroepithelial neoplasms representing about 0,2% to 2% of all breast tumors with an incidence of about 2.1 per million. The classification proposed by the World Health Organization for PTs into benign, borderline, and malignant is based on a combination of several histologic features. High-grade malignant phyllodes tumors may spread by hematogenous route. While smaller and moderate size malignant phyllodes may typically be seen, gigantic ones with larger than 10 cm in diameter are very rare. We report an unusual case of a giant malignant phyllodes tumor with metastases that grew over a 6 years period causing significant ulceration, body disfigurement and physical transformation. Our experience indicated that surgical treatment of malignant phyllodes tumor might be an option for improving patients' quality of life, regardless of the extremely poor prognosis.

KEY WORDS

Breast, Malignant phyllodes tumor, Surgical treatment.

摘要

摘要

叶状肿瘤(PTs)是罕见的纤维上皮性肿瘤,约占所有乳腺肿瘤的0.2%至2%,发病率约为百万分之2.1。世界卫生组织对PTs的分类为良性、交界性和恶性,是基于多种组织学特征的综合判断。高级别恶性叶状肿瘤可通过血行途径转移。虽然通常可见较小和中等大小的恶性叶状肿瘤,但直径大于10 cm的巨大肿瘤非常罕见。我们报告了一例不寻常的巨大恶性叶状肿瘤伴转移的病例,该肿瘤在6年时间里生长,导致严重溃疡、身体畸形和外形改变。我们的经验表明,恶性叶状肿瘤的手术治疗可能是改善患者生活质量的一种选择,尽管预后极差。

关键词

乳腺;恶性叶状肿瘤;手术治疗

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