Choi Jun-Chul, Yuan Hao-Yu, Fukaya Norihisa, Onozawa Syun-Ya, Zhang Qiao, Choi Seong Jib, Yasuda Hiroyuki
National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8573, Japan.
Chem Asian J. 2017 Jun 19;12(12):1297-1300. doi: 10.1002/asia.201700465. Epub 2017 May 17.
A direct synthesis of carbamates from amines and carbon dioxide in the presence of Ti(OR) (R=nBu (1), Me (2), Et (3), nPr (4)) was investigated. Aniline was reacted with titanium n-butoxide (1) in the presence of carbon dioxide (5 MPa) to give the corresponding n-butyl N-phenylcarbamate (BPC) in nearly quantitative yield (99 %) within 20 min. Furthermore, 1 could be regenerated upon reaction with n-butanol during water removal. The recovered 1 could then be reused in a subsequent reaction.
研究了在Ti(OR)（R = 正丁基(1)、甲基(2)、乙基(3)、正丙基(4)）存在下，胺与二氧化碳直接合成氨基甲酸酯的反应。苯胺在二氧化碳（5 MPa）存在下与正丁醇钛(1)反应，在20分钟内以近乎定量的产率（99%）得到相应的N-苯基正丁基氨基甲酸酯（BPC）。此外，在脱水过程中与正丁醇反应时，1可以再生。回收的1然后可在后续反应中重复使用。
