[Na,K-ATPase activity of erythrocyte ghosts of mammals in the presence of alamethicin and p-nitrophenylphosphate].

After preincubation of erythrocyte ghosts isolated from Sprague-Dawley rats activity of Na, K-ATPase was more successfully manifested, being elevated about 2.5-fold, while the ratio Mg-ATPase/Na, K-ATPase was decreased 3-fold. Optimal ratio of alamethicin/protein was equal to 0.3. The similar results were obtained if p-nitrophenyl phosphate, easily penetrating through the erythrocyte membrane, was used as an exogenous substrate.