Sokol'nikov A A, Kodentsova V M, Gulidova G P, Mironova G D
Vopr Med Khim. 1988 Mar-Apr;34(2):53-6.
After preincubation of erythrocyte ghosts isolated from Sprague-Dawley rats activity of Na, K-ATPase was more successfully manifested, being elevated about 2.5-fold, while the ratio Mg-ATPase/Na, K-ATPase was decreased 3-fold. Optimal ratio of alamethicin/protein was equal to 0.3. The similar results were obtained if p-nitrophenyl phosphate, easily penetrating through the erythrocyte membrane, was used as an exogenous substrate.
对从Sprague-Dawley大鼠分离出的红细胞血影进行预孵育后，Na,K-ATP酶的活性得到更显著的体现，提高了约2.5倍，而Mg-ATP酶与Na,K-ATP酶的比率降低了3倍。阿拉米辛与蛋白质的最佳比率为0.3。如果使用易于穿透红细胞膜的对硝基苯磷酸酯作为外源底物，也可得到类似结果。
