Kawai K, Fukuda K, Tsuchiyama H
Second Department of Pathology, Nagasaki University, School of Medicine, Japan.
Acta Pathol Jpn. 1988 Apr;38(4):531-40. doi: 10.1111/j.1440-1827.1988.tb02326.x.
A rare case of malacoplakia (MKP) of the endometrium in an 88-year-old Japanese woman is presented. By light microscopy, typical Michaelis-Gutmann bodies (M-G bodies) could be identified. Electron microscopic findings revealed M-G bodies in various stages of development. These features suggested that M-G bodies were derived from round electron-dense granules that coalesced to form phagolysosomes. Early-stage M-G bodies were manifested as small, irregular, needle-shaped areas of calcification in phagolysosomes. The present paper reviews 6 cases of endometrial MKP, 5 of which have previously been reported in the literature, and this case being the sixth, to our knowledge.
本文报告了一例88岁日本女性子宫内膜软斑病（MKP）的罕见病例。通过光学显微镜检查，可以识别出典型的米氏小体（M-G小体）。电子显微镜检查结果显示了处于不同发育阶段的M-G小体。这些特征表明，M-G小体源自圆形电子致密颗粒，这些颗粒融合形成吞噬溶酶体。早期的M-G小体表现为吞噬溶酶体中微小、不规则、针状的钙化区域。本文回顾了6例子宫内膜MKP病例，据我们所知，其中5例此前已在文献中报道，本病例为第6例。
