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益生菌LbP2对患犬瘟热相关性腹泻犬临床参数的影响。

Effect of the probiotic LbP2 on clinical parameters of dogs with distemper-associated diarrhea.

作者信息

Delucchi Luis, Fraga Martín, Zunino Pablo

机构信息

Departamento de Patología y Clínica de Pequeños Animales, Facultad de Veterinaria, Universidad de la República, Lasplaces 1550, CP 11600, Montevideo, Uruguay (Delucchi); Departamento de Microbiología, Instituto de Investigaciones Biológicas Clemente Estable, Avenida Italia 3318, CP 11600, Montevideo, Uruguay (Fraga, Zunino).

出版信息

Can J Vet Res. 2017 Apr;81(2):118-121.

Abstract

The objective of this study was to assess the effect of the probiotic native strain (LbP2) on general clinical parameters of dogs with distemper-associated diarrhea. Two groups of dogs over 60 d of age with distemper and diarrhea were used in the study, which was done at the Animal Hospital of the Veterinary Faculty of the University of Uruguay, Montevideo, Uruguay. The dogs were treated orally each day for 5 d with the probiotic or with a placebo (vehicle without bacteria). Clinical parameters were assessed and scored according to a system specially designed for this study. Blood parameters were also measured. Administration of the probiotic significantly improved the clinical score of the patients, whereas administration of the placebo did not. Stool output, fecal consistency, mental status, and appetite all improved in the probiotic-treated dogs. These results support previous findings of beneficial effects with the probiotic LbP2 in dogs. Thus, combined with other therapeutic measures, probiotic treatment appears to be promising for the management of canine distemper-associated diarrhea.

摘要

本研究的目的是评估益生菌本地菌株(LbP2)对患犬瘟热相关性腹泻犬的一般临床参数的影响。本研究使用了两组60日龄以上患犬瘟热和腹泻的犬,研究在乌拉圭蒙得维的亚乌拉圭大学兽医学院动物医院进行。这些犬每天口服益生菌或安慰剂(不含细菌的赋形剂),持续5天。根据专门为本研究设计的系统对临床参数进行评估和评分。还测量了血液参数。给予益生菌显著改善了患者的临床评分,而给予安慰剂则没有。接受益生菌治疗的犬的粪便排出量、粪便稠度、精神状态和食欲均有所改善。这些结果支持了之前关于益生菌LbP2对犬有益作用的研究结果。因此,结合其他治疗措施,益生菌治疗似乎有望用于治疗犬瘟热相关性腹泻。

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