Wang Jin-Hui, Cui Shan
Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
College of Life Sciences, Chinese Academy of Sciences, Beijing, 100101, China.
F1000Res. 2017 Mar 17;6:283. doi: 10.12688/f1000research.11096.2. eCollection 2017.
Associative learning and memory are common activities in life, and their cellular infrastructures constitute the basis of cognitive processes. Although neuronal plasticity emerges after memory formation, basic units and their working principles for the storage and retrieval of associated signals remain to be revealed. Current reports indicate that associative memory cells, through their mutual synapse innervations among the co-activated sensory cortices, are recruited to fulfill the integration, storage and retrieval of multiple associated signals, and serve associative thinking and logical reasoning. In this review, we aim to summarize associative memory cells in their formation, features and functional impacts.
联想学习和记忆是生活中的常见活动,它们的细胞基础构成了认知过程的基础。尽管神经元可塑性在记忆形成后出现,但相关信号存储和检索的基本单元及其工作原理仍有待揭示。目前的报告表明,联想记忆细胞通过共同激活的感觉皮层之间的相互突触支配,被招募来完成多个相关信号的整合、存储和检索,并服务于联想思维和逻辑推理。在这篇综述中,我们旨在总结联想记忆细胞的形成、特征和功能影响。