全膝关节置换术后血清C反应蛋白水平的评估。
Evaluation of serum levels of C-reactive protein after total knee arthroplasty.
作者信息
Barretto João Maurício, Loures Fabrício Bolpato, Albuquerque Rodrigo Sattamini Pires E, Bezerra Filipe das Neves, Faro Rafael Vinagre, Cavanellas Naasson Trindade
机构信息
Instituto Nacional de Traumatologia e Ortopedia (Into), Rio de Janeiro, RJ, Brazil.
出版信息
Rev Bras Ortop. 2017 Mar 6;52(2):176-181. doi: 10.1016/j.rboe.2016.05.009. eCollection 2017 Mar-Apr.
OBJECTIVE
To evaluate the behavior of C-reactive protein (CRP) levels in the first three weeks after total knee arthroplasty (TKA) and define the factors related to its variation.
METHODS
We evaluated the CRP values in 103 patients undergoing primary TKA. Serum CRP was measured on the day before surgery, and on the third and twenty-first days after the procedure.
RESULTS
PCR showed sudden increase on the third day after surgery, reaching the mean value of 111.9 mg/L, median 75.9 mg/L. Only one-third of the patients returned to normal levels in the third week. In the immediate postoperative period, CRP was not correlated with body mass index (BMI), age, gender, blood transfusion, or complications.
CONCLUSION
Serum CRP remains high in the third week after TKA in most patients, and this change is primarily related to surgical trauma.
目的
评估全膝关节置换术（TKA）后前三周C反应蛋白（CRP）水平的变化情况，并确定与其变化相关的因素。
方法
我们评估了103例行初次TKA患者的CRP值。在手术前一天以及术后第三天和第二十一天测量血清CRP。
结果
CRP在术后第三天突然升高，平均值达到111.9mg/L，中位数为75.9mg/L。只有三分之一的患者在第三周恢复到正常水平。在术后即刻，CRP与体重指数（BMI）、年龄、性别、输血或并发症无关。
结论
大多数患者在TKA后第三周血清CRP仍维持在较高水平，这种变化主要与手术创伤有关。
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