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Radioguided occult lesion localization for locally recurrent thyroid carcinoma.

作者信息

Gulcelik Mehmet Ali, Karaman Niyazi, Dogan Lutfi, Sahiner Ilgın, Akgul Gokhan Giray, Kahraman Yavuz Selim, Vural Gulin Ucmak

机构信息

Department of General Surgery, Ankara Oncology Training and Research Hospital, Angora Evleri Ressamlar Caddesi F6 Blok No 8, Beysukent, 06800, Ankara, Turkey.

Department of Nuclear Medicine, Ankara Oncology Training and Research Hospital, Ankara, Turkey.

出版信息

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2915-2919. doi: 10.1007/s00405-017-4563-2. Epub 2017 Apr 13.

DOI:10.1007/s00405-017-4563-2
PMID:28409262
Abstract

The aim of this study was to present our experiences with patients operated on for the recurrence of papillary thyroid cancer with the combined use of preoperative ultrasonographic mapping and radioguided occult lesion localization (ROLL). Twenty patients who had already undergone total thyroidectomy and central/lateral neck dissection for papillary thyroid carcinoma were reoperated on due to locoregional metastasis. The patients with proven recurrences and high Tg wash-out levels in cytopathologic aspirates were operated on. For each patient, numbers of marked and non-marked lesions, and the metastatic and total numbers of marked/non-marked and non-mentioned lesions in the maps were recorded. Thirty-four of 40 (85%) lesions removed with ROLL were found to be malignant. In addition to the marked lesions during mapping, 60 additional lesions had been defined as suspicious. Fifty-six of these lesions were found at exact anatomic sites and localizations described and removed. Of 56 lesions, 36 (64%) were found to be metastatic. During postoperative follow-up, chylous leak with spontaneous regression in 7 days and seroma occurred in one patient. Radioguided occult lesion localization and preoperative mapping contribute to the safety and comfort of patients in planned reoperations on lateral and central neck regions.

摘要

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引用本文的文献

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Radioguided localization of recurrent lymph nodes in differentiated thyroid cancer - Where are we now?

本文引用的文献

1
Surgical targeting of recurrent thyroid cancer using a novel mixture of 99m-technetium macroaggregated albumin and indocyanine green.使用99m-锝标记的大颗粒白蛋白和吲哚菁绿的新型混合物对复发性甲状腺癌进行手术靶向治疗。
Surg Innov. 2014 Dec;21(6):622-9. doi: 10.1177/1553350614524840. Epub 2014 Mar 10.
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Radioguided occult lesion localization of cervical recurrences from differentiated thyroid cancer: technical feasibility and clinical results.放射性引导下分化型甲状腺癌颈部复发隐匿性病变的定位:技术可行性及临床结果
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3
Combination of preoperative ultrasonographic mapping and radioguided occult lesion localization in patients with locally recurrent/persistent papillary thyroid carcinoma: a practical method for central compartment reoperations.
分化型甲状腺癌复发淋巴结的放射性引导定位——我们目前的进展如何?
Arch Endocrinol Metab. 2018 Oct;62(5):491-492. doi: 10.20945/2359-3997000000079.
术前超声绘图与放射性核素导向隐匿性病灶定位在局部复发性/持续性甲状腺乳头状癌患者中的联合应用:一种中央区再次手术的实用方法。
Clin Nucl Med. 2010 Nov;35(11):847-52. doi: 10.1097/RLU.0b013e3181f48403.
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A new radioguided procedure for localization and surgical treatment of neck node metastasis of papillary thyroid cancer.一种新的放射性导向程序,用于定位和手术治疗甲状腺乳头状癌颈部淋巴结转移。
J Endocrinol Invest. 2010 May;33(5):339-42. doi: 10.1007/BF03346596. Epub 2009 Dec 22.
5
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.美国甲状腺协会修订的甲状腺结节和分化型甲状腺癌患者管理指南。
Thyroid. 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110.
6
Combined use of perioperative TSH-stimulated (18)F-FDG PET/CT imaging and gamma probe radioguided surgery to localize and verify resection of iodine scan-negative recurrent thyroid carcinoma.围手术期促甲状腺激素刺激的(18)F-FDG PET/CT成像与γ探针放射性核素引导手术联合应用以定位和验证碘扫描阴性复发性甲状腺癌的切除情况。
Laryngoscope. 2008 Dec;118(12):2190-4. doi: 10.1097/MLG.0b013e3181845738.
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Radio-guided nonpalpable metastatic lymph node localization in patients with recurrent thyroid cancer.
J Surg Oncol. 2007 Nov 1;96(6):534-8. doi: 10.1002/jso.20873.
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