Cerit Ethem Turgay, Yalçin Mehmet Muhittin, Ӧzkan Çiğdem, Aktürk Müjde, Altinova Alev Eroğlu, Akdemir Ümit Ӧzgür, Akin Murat, Arslan Emre, Karakoç Ayhan, Çimen Ali Riza, Çakir Nuri
Department of Endocrinology and Metabolism, Faculty of Medicine, Gazi University, Ankara, Turkey.
Department of Nuclear Medicine, Faculty of Medicine, Gazi University, Ankara, Turkey.
Arch Endocrinol Metab. 2018 Oct;62(5):495-500. doi: 10.20945/2359-3997000000068.
Our aim was to present our experiences related to performing neck surgery using the guided intraoperative scintigraphic tumor targeting (GOSTT) procedure for patients who had locally recurrent or persistent differentiated thyroid cancer (DTC) and who had undergone previous thyroid surgery.
We retrospectively evaluated 11 patients who had locally recurrent or persistent DTC, who had undergone previous surgery, and for whom reoperation was planned for metastatic cervical lymph nodes (LNs). We performed the neck surgery using the GOSTT procedure on all patients and at a single academic institution.
The 11 patients had a total of 26 LNs, as marked with a radiotracer, and those LNs' mean size was 14.7 ± 8.2 mm (range: 5-34 mm). Histopathological examinations revealed DTC metastasis in all 26 of the preoperatively marked LNs. Of the 11 patients, only one needed a reoperation in the neck; she had another successful surgery (also using the GOSTT procedure). In the evaluation of the patients' final status, all were disease-free in their necks. There also were no GOSTT-associated postoperative complications.
The GOSTT procedure is a useful, successful, inexpensive, and comfortable procedure for marking and mapping metastatic LNs, especially in DTC patients who have undergone previous surgery.
我们的目的是介绍对于局部复发或持续性分化型甲状腺癌（DTC）且曾接受过甲状腺手术的患者，使用术中放射性核素肿瘤靶向引导（GOSTT）程序进行颈部手术的相关经验。
我们回顾性评估了11例局部复发或持续性DTC患者，这些患者均曾接受过手术，且计划对转移性颈部淋巴结（LN）进行再次手术。我们在单一学术机构对所有患者均采用GOSTT程序进行颈部手术。
11例患者共有26个经放射性示踪剂标记的LN，这些LN的平均大小为14.7±8.2毫米（范围：5 - 34毫米）。组织病理学检查显示，术前标记的所有26个LN均有DTC转移。11例患者中，只有1例需要再次进行颈部手术；她再次成功接受了手术（同样采用GOSTT程序）。在评估患者的最终状态时，所有患者颈部均无疾病。也没有与GOSTT相关的术后并发症。
GOSTT程序是一种用于标记和定位转移性LN的有用、成功、廉价且舒适的程序，尤其适用于曾接受过手术的DTC患者。
