Weng Yi-Hao, Yang Chun-Yuh, Chiu Ya-Wen
a Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital , Chang Gung University College of Medicine , Taipei , Taiwan.
b Department of Public Health , Kaohsiung Medical University , Kaohsiung , Taiwan.
Arch Environ Occup Health. 2018 Jan 2;73(1):48-55. doi: 10.1080/19338244.2017.1299084. Epub 2017 Apr 14.
This study investigated the temperature-specific risks of adverse neonatal outcomes in Taiwan. Over 2 million births between 2001 and 2010 were correlated with the daily mean outdoor temperatures at birth. A log-binomial model was used to estimate the risk of adverse neonatal outcomes in relation to ambient temperature at birth after adjusting for possible confounders. There was a significant correlation of temperature extremes with stillbirth, preterm birth, and low birth weight. Maternal exposure to temperature extremes carried greater risks of stillbirth (> 23.4°C), preterm birth (< 19.5°C and > 25.4°C), and low birth weight (< 15.5°C and > 23.4°C) than did temperatures of 21.5°C∼23.4°C. In conclusion, infants born to women exposed to temperature extremes possess greater risks for stillbirth, preterm birth, and low birth weight. The data suggest optimal temperatures to minimize overall adverse neonatal outcomes are 21.5°C∼23.4°C.
本研究调查了台湾地区新生儿不良结局的特定温度风险。2001年至2010年间超过200万例分娩与出生时的每日平均室外温度相关。在对可能的混杂因素进行调整后，使用对数二项模型来估计出生时环境温度与新生儿不良结局的风险。极端温度与死产、早产和低出生体重之间存在显著相关性。与21.5°C至23.4°C的温度相比，母亲暴露于极端温度下发生死产（>23.4°C）、早产（<19.5°C和>25.4°C）和低出生体重（<15.5°C和>23.4°C）的风险更高。总之，母亲暴露于极端温度下所生婴儿出现死产、早产和低出生体重的风险更高。数据表明，将总体新生儿不良结局降至最低的最佳温度为21.5°C至23.4°C。
