美国医疗服务不足人群中HPV感染率和宫颈癌发病率的差异。
Disparity in rates of HPV infection and cervical cancer in underserved US populations.
作者信息
Karuri Asok Ranjan, Kashyap Vivek Kumar, Yallapu Murali Mohan, Zafar Nadeem, Kedia Satish K, Jaggi Meena, Chauhan Subhash C
机构信息
Department of Pharmaceutical Sciences and Cancer Research Center, University of Tennessee Health Science Center, Memphis, Tennessee, USA, 38163.
Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA, 38163.
出版信息
Front Biosci (Schol Ed). 2017 Jun 1;9(2):254-269. doi: 10.2741/s486.
Abstract
There is a higher rate of HPV infection and cervical cancer incidence and mortality in underserved US population who reside in Appalachian mountain region compared to Northern Plains. Social and behavioral factors such as smoking and alcohol consumption are for such a high incidence. However, by and large, the reasons for these discrepancies lie in the reluctance of the underserved population to adopt preventive measures such as prophylactic Human papilloma virus (HPV) vaccines and Pap smear screening that have significantly reduced the incidence and mortality rate of cervical cancer in Caucasian women. Thus, it is clear that drastic change in social behavior and implementation of preventive measures is required to effectively reduce the incidence and mortality from cervical cancer in this underserved population.
摘要
与北部平原地区相比，居住在美国阿巴拉契亚山区服务不足人群中的人乳头瘤病毒（HPV）感染率、宫颈癌发病率和死亡率更高。吸烟和饮酒等社会和行为因素导致了如此高的发病率。然而，总体而言，这些差异的原因在于服务不足人群不愿采取预防性措施，如预防性人乳头瘤病毒（HPV）疫苗接种和巴氏涂片筛查，而这些措施已显著降低了白人女性宫颈癌的发病率和死亡率。因此，很明显，需要社会行为的巨大改变和预防性措施的实施，以有效降低这一服务不足人群中宫颈癌的发病率和死亡率。
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