Carlson R W, Bowles A L, Haupt M T
Division of Pulmonary/Critical Care Medicine, Wayne State University School of Medicine, Detroit, Michigan.
Crit Care Clin. 1986 Apr;2(2):347-72.
Anaphylactic, anaphylactoid, and related forms of shock are true medical emergencies characterized by bronchial reactivity, airway edema, and hypovolemia. These reactions are attributed to the immunologic and nonimmunologic activation of mast cells and basophils, which results in the acute release of a variety of biochemical mediators that influence vascular tone and permeability. The therapeutic approach to these reactions is guided by the understanding of associated cellular and biochemical changes.
过敏性、类过敏性及相关形式的休克是真正的医疗急症，其特征为支气管反应性、气道水肿和血容量不足。这些反应归因于肥大细胞和嗜碱性粒细胞的免疫性和非免疫性激活，这会导致多种影响血管张力和通透性的生化介质急性释放。针对这些反应的治疗方法以对相关细胞和生化变化的理解为指导。
