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[IFE:一种从在尼日利亚、喀麦隆和中非共和国捕获的锤头果蝠中分离出的新型非洲环状病毒]

[IFE: a new African orbivirus isolated from Eidolon helvum bats captured in Nigeria, Cameroon and the Central African Republic].

作者信息

Kemp G E, Le Gonidec G, Karabatsos N, Rickenbach A, Cropp C B

机构信息

Centre des Maladies Infectieuses, Center for disease Control, Fort-Collins, Colorado 80522.

出版信息

Bull Soc Pathol Exot Filiales. 1988;81(1):40-8.

PMID:2841044
Abstract

Eight viral isolates were recovered from Eidolon helvum bats collected in Nigeria and Cameroon in 1971 and from the Central African Republic in 1974. Subsequent studies showed that the agents from the three countries were similar and were strains of a new virus of the Orbivirus genus, family Reoviridae. This new virus was characterized with respect to its sensitivity to lipid solvents and to pH, its relative size and morphology by electron microscopy, its effect on mice experimentally infected by various routes, the histopathology found in infected mice, and its antigenic relationship or lack of a relationship to other known orbiviruses.

摘要

1971年从尼日利亚和喀麦隆采集的锤头果蝠以及1974年从中非共和国采集的锤头果蝠中分离出了8种病毒株。随后的研究表明,来自这三个国家的病原体相似,是呼肠孤病毒科环状病毒属的一种新病毒的毒株。对这种新病毒的特性进行了如下研究:对脂质溶剂和pH的敏感性、通过电子显微镜观察其相对大小和形态、对经各种途径实验感染的小鼠的影响、感染小鼠的组织病理学,以及它与其他已知环状病毒的抗原关系或无抗原关系。

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