Mitter Sumeet S, Yancy Clyde W
Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL 60611, USA.
Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL 60611, USA.
Cardiol Clin. 2017 May;35(2):261-271. doi: 10.1016/j.ccl.2016.12.008.
Incident heart failure and the burden of hospitalization may be demonstrating a decline. However, as the population ages, the prevalence of heart failure continues to increase. Mortality among heart failure patients is increasingly due to non-cardiovascular causes. Current evidence-based therapy for heart failure has improved heart failure related mortality. Current efforts should be directed toward optimizing evidence based medical and device therapy, reducing morbidity, and increasing quality of life with heart failure. Future clinical trials should focus on therapies for heart failure with preserved ejection fraction, regenerative therapy for heart failure, and optimizing durable mechanical support for end-stage heart failure.
新发心力衰竭及住院负担可能呈下降趋势。然而，随着人口老龄化，心力衰竭的患病率持续上升。心力衰竭患者的死亡越来越多地归因于非心血管原因。目前基于证据的心力衰竭治疗已降低了与心力衰竭相关的死亡率。当前的努力应致力于优化基于证据的药物和器械治疗，降低发病率，并提高心力衰竭患者的生活质量。未来的临床试验应聚焦于射血分数保留的心力衰竭治疗、心力衰竭的再生治疗，以及优化终末期心力衰竭的长期机械支持。
