Service d'otorhinolaryngologie et chirurgie cervico-faciale, centre hospitalier régional universitaire de Besançon, 2, boulevard Fleming, 25030 Besançon, France.
Service d'otorhinolaryngologie et chirurgie cervico-faciale, centre hospitalier régional universitaire de Besançon, 2, boulevard Fleming, 25030 Besançon, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2017 Dec;134(6):427-430. doi: 10.1016/j.anorl.2017.03.005. Epub 2017 Apr 12.
Vagal paraganglioma are rare tumors that are mostly asymptomatic. We report a case of vagal paraganglioma associated with paraneoplastic polymyalgia rheumatica and review the literature on benign paragangliomas of the head and neck associated with paraneoplastic syndrome.
A 53-year-old man presented with atypical polymyalgia rheumatica. MRI revealed a tumor that was then surgically excised. Histological examination confirmed the diagnosis of benign vagal paraganglioma. Rapid, complete and permanent resolution of all rheumatological symptoms were observed postoperatively, confirming the diagnosis of paraneoplastic polymyalgia rheumatica.
Paraganglioma of the neck associated with paraneoplastic syndrome remains exceptional. A predisposing gene mutation must be systematically investigated. Long-term surveillance must be ensured due to the risk of local recurrence, second tumors or metastasis.
迷走神经副神经节瘤是一种罕见的肿瘤，大多无症状。我们报告了一例迷走神经副神经节瘤伴副肿瘤性巨细胞性多关节炎，并复习了与副肿瘤综合征相关的头颈部良性副神经节瘤的文献。
一名 53 岁男性表现为非典型性巨细胞性多关节炎。MRI 显示肿瘤，随后手术切除。组织学检查证实为良性迷走神经副神经节瘤的诊断。术后所有风湿症状迅速、完全和永久性缓解，证实了副肿瘤性巨细胞性多关节炎的诊断。
与副肿瘤综合征相关的颈部副神经节瘤仍然罕见。必须系统地调查潜在的基因突变。由于局部复发、第二肿瘤或转移的风险，必须确保长期随访。
